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High-efficacy therapies for treatment-naïve individuals with relapsing–remitting multiple sclerosis
There are> 18 distinct disease-modifying therapy (DMT) options covering 10 mechanisms of
action currently approved by the US Food and Drug Administration for the treatment of …
action currently approved by the US Food and Drug Administration for the treatment of …
Multiple sclerosis: time for early treatment with high-efficacy drugs
This review addresses current changes in the approach to treating patients with multiple
sclerosis (MS). The widely practiced approach of utilizing agents with lower treatment …
sclerosis (MS). The widely practiced approach of utilizing agents with lower treatment …
[HTML][HTML] Monoclonal antibodies in the treatment of relapsing multiple sclerosis: an overview with emphasis on pregnancy, vaccination, and risk management
N Krajnc, G Bsteh, T Berger, J Mares, HP Hartung - Neurotherapeutics, 2022 - Elsevier
Monoclonal antibodies have become a mainstay in the treatment of patients with relapsing
multiple sclerosis (RMS) and provide some benefit to patients with primary progressive MS …
multiple sclerosis (RMS) and provide some benefit to patients with primary progressive MS …
The risk of infections for multiple sclerosis and neuromyelitis optica spectrum disorder disease-modifying treatments: Eighth European Committee for Treatment and …
Over the recent years, the treatment of multiple sclerosis (MS) and neuromyelitis optica
spectrum disorder (NMOSD) has evolved very rapidly and a large number of disease …
spectrum disorder (NMOSD) has evolved very rapidly and a large number of disease …
Personalized use of disease-modifying therapies in multiple sclerosis
CY Lee, KH Chan - Pharmaceutics, 2024 - mdpi.com
Multiple sclerosis is an important neurological disease affecting millions of young patients
globally. It is encouraging that more than ten disease-modifying drugs became available for …
globally. It is encouraging that more than ten disease-modifying drugs became available for …
Treatment of patients with multiple sclerosis transitioning between relapsing and progressive disease
NG Dimitriou, SG Meuth, EH Martinez-Lapiscina… - CNS drugs, 2023 - Springer
Multiple sclerosis (MS) is a chronic autoimmune demyelinating and neurodegenerative
disease of the central nervous system with a wide variety of clinical phenotypes. In spite of …
disease of the central nervous system with a wide variety of clinical phenotypes. In spite of …
Safety and efficacy with alemtuzumab over 13 years in relapsing-remitting multiple sclerosis: final results from the open-label TOPAZ study
AJ Coles, A Achiron, A Traboulsee… - Therapeutic …, 2023 - journals.sagepub.com
Background and objectives: Alemtuzumab demonstrated superior efficacy versus
subcutaneous interferon (IFN) beta-1a in participants with relapsing-remitting multiple …
subcutaneous interferon (IFN) beta-1a in participants with relapsing-remitting multiple …
Antibody-mediated cell depletion therapies in multiple sclerosis
A Mariottini, PA Muraro, JD Lünemann - Frontiers in Immunology, 2022 - frontiersin.org
Development of disease-modifying therapies including monoclonal antibody (mAb)-based
therapeutics for the treatment of multiple sclerosis (MS) has been extremely successful over …
therapeutics for the treatment of multiple sclerosis (MS) has been extremely successful over …
Expert narrative review of the safety of cladribine tablets for the management of relapsing multiple sclerosis
P Clavelou, G Castelnovo, V Pourcher, J De Sèze… - Neurology and …, 2023 - Springer
Cladribine tablets (CladT) is a highly active oral disease-modifying therapy (DMT) for the
management of relapsing multiple sclerosis (RMS). CladT acts as an immune reconstitution …
management of relapsing multiple sclerosis (RMS). CladT acts as an immune reconstitution …
Sustained reduction of serum neurofilament light chain over 7 years by alemtuzumab in early relapsing–remitting MS
Background: Alemtuzumab efficacy and safety was demonstrated in CARE-MS I and
extension studies (CAMMS03409; TOPAZ). Objective: Evaluate serum neurofilament light …
extension studies (CAMMS03409; TOPAZ). Objective: Evaluate serum neurofilament light …