[HTML][HTML] The unique immune evasion mechanisms of the mpox virus and their implication for develo** new vaccines and immunotherapies

D Fang, Y Liu, D Dou, B Su - Virologica Sinica, 2024 - Elsevier
Mpox is an infectious and contagious zoonotic disease caused by the mpox virus (MPXV),
which belongs to the genus Orthopoxvirus. Since 2022, MPXV has posed a significant threat …

[HTML][HTML] Recent Advancements in mRNA Vaccines: From Target Selection to Delivery Systems

Z Wu, W Sun, H Qi - Vaccines, 2024 - mdpi.com
mRNA vaccines are leading a medical revolution. mRNA technologies utilize the host's own
cells as bio-factories to produce proteins that serve as antigens. This revolutionary approach …

Virus-like particle vaccines with epitopes from porcine epidemic virus and transmissible gastroenteritis virus incorporated into self-assembling ADDomer platform …

P Du, Q Yan, XA Zhang, W Zeng, K **e, Z Yuan… - Frontiers in …, 2023 - frontiersin.org
Introduction Porcine epidemic diarrhea virus (PEDV) and transmissible gastroenteritis virus
(TGEV) are major intestinal coronaviruses that cause vomiting, diarrhea, dehydration, and …

Immunoinformatics-based multi-epitope vaccine design for the re-emerging monkeypox virus

M Farzan, M Farzan, Y Mirzaei, S Aiman… - International …, 2023 - Elsevier
Abstract Background On May 7, 2022, WHO reported a new monkeypox case. By May 2023
over 80,000 cases had been reported worldwide outside previously endemic nations.(This …

Deciphering the immunogenicity of monkeypox proteins for designing the potential mRNA vaccine

M Shah, S Jaan, M Shehroz, A Sarfraz, K Asad… - ACS …, 2023 - ACS Publications
The Monkeypox virus (MPXV), an orthopox virus, is responsible for monkeypox in humans, a
zoonotic disease similar to smallpox. This infection first appeared in the 1970s in humans …

Bioinformatics and immunoinformatics approach to develop potent multi-peptide vaccine for coxsackievirus B3 capable of eliciting cellular and humoral immune …

A Ullah, M Waqas, S Aziz, S ur Rahman, S Khan… - International Journal of …, 2023 - Elsevier
Abstract Coxsackievirus B3 (CVB3) is a viral pathogen of various human disorders with no
effective preventative interventions. Herein, we aimed to design a chimeric vaccine construct …

Pharmacological treatment and vaccines in monkeypox virus: a narrative review and bibliometric analysis

MA Shamim, P Satapathy, BK Padhi… - Frontiers in …, 2023 - frontiersin.org
Mpox (earlier known as monkeypox) virus infection is a recognized public health
emergency. There has been little research on the treatment options. This article reviews the …

[HTML][HTML] Immunoinformatics Design of a Multiepitope Vaccine (MEV) Targeting Streptococcus mutans: A Novel Computational Approach

RS Naorem, BD Pangabam, SS Bora, C Fekete… - Pathogens, 2024 - mdpi.com
Dental caries, a persistent oral health challenge primarily linked to Streptococcus mutans,
extends its implications beyond dental decay, affecting over 4 billion individuals globally …

Proteomic profiling of membrane vesicles from Mycobacterium avium subsp. paratuberculosis: Navigating towards an in silico design of a multi-epitope vaccine …

JJ Lee, M Abdullah, J Liu, IA Carvalho, AS Junior… - Journal of …, 2024 - Elsevier
Bacteria typically produce membrane vesicles (MVs) at varying levels depending on the
surrounding environments. Gram-negative bacterial outer membrane vesicles (OMVs) have …

In silico designing a novel TLR4-mediating multiepitope vaccine against monkeypox via advanced immunoinformatics and bioinformatics approaches

MR Lahimchi, H Madanchi, K Ahmadi… - Journal of …, 2024 - Taylor & Francis
Monkeypox virus is a member of the Poxviridae family, which causes monkeypox zoonotic
disease. Since July 2022, the prevention of monkeypox have become more considerable …