Evolutionary game theory mathematically conceptualizes and analyzes biological
interactions where one's fitness not only depends on one's own traits, but also on the traits of …

In metastatic castrate resistant prostate cancer (mCRPC), abiraterone is conventionally
administered continuously at maximal tolerated dose until treatment failure. The majority of …

We derive and analyse a deterministic model for the transmission of malaria disease with
mass action form of infection. Firstly, we calculate the basic reproduction number, R0, and …

In this paper, we present a model for onchocerciasis that considers mass administration of
ivermectin, contact prevention controls and vector elimination. The model equilibria are …

Cancer is a highly heterogeneous disease, exhibiting spatial and temporal variations that
pose challenges for designing robust therapies. Here, we propose the VEPART (Virtual …

This chapter is devoted to models of cancer growth and anticancer therapies that put special
emphasis on the dependence of therapy efficiency on cell cycle. First, biological background …

The aim of this paper is to investigate the effectiveness and cost-effectiveness of
leptospirosis control measures, preventive vaccination and treatment of infective humans …

Over the past decade, several targeted therapies (eg imatinib, dasatinib, nilotinib) have
been developed to treat Chronic Myeloid Leukemia (CML). Despite an initial response to …

The paper is devoted to the study of a mathematical model of drug therapy for Chronic
Myelogenous Leukemia (CML). The disease dynamics are given by a couple of delay …

Leukaemia accounts for around 3% of all cancer types diagnosed in adults, and is the most
common type of cancer in children of paediatric age (typically ranging from 0 to 14 years) …