The clinical effectiveness of the available anticancer drugs has been reduced due to the
development of drug resistance and serious adverse effects, which have restricted …

Accumulating evidence indicates that the anticancer activity of acridine derivatives is
mediated through the regulation of anti-apoptotic and pro-apoptotic BCL2 protein …

An increasing amount of sewage has been discharged into water bodies in the progression
of industrialization and urbanization, causing serious water pollution. Meanwhile, the …

A novel synthetic reaction was employed to produce an acridine derivative of 4-ethyl
acridine-1, 3, 9 (2, 4, 10H)-trione. The structural characterizations of the synthesized …

Herein, we report a metal-free and efficient method for the C (sp3)–H functionalization of 1,
2, 3, 4-tetrahydroacridines at the C4-position by the addition of azodicarboxylates (C–N …

Calicheamicin γ1 and related natural products are renowned for their potency in DNA
cleavage, serving as the warheads in commercial ADCs used for treating leukemia. Their …

This study focuses on the synthesis and structural characterization of new compounds that
integrate thiazolidine-2, 4-dione, acridine moiety, and an acetamide linker, aiming to …

Mixed-ligand complexes of cobalt (II) with two bioligands, viz. 2-picolinehydroxamic acid and
the reduced Schiff base N-(2-hydroxybenzyl) phenylalanine, were studied in aqueous …

In this study, a highly efficient green synthetic protocol was developed for the synthesis of
spiroacridines and spiroquinolines via a multicomponent reaction of 3, 4 …

Phenylacridine (9‐PA) is an important acridine‐based medicine that has been proven to
possess significant anticancer activity and can be used as a photodynamic therapy (PDT) …