Demographic history, selection and functional diversity of the canine genome

EA Ostrander, RK Wayne, AH Freedman… - Nature Reviews …, 2017 - nature.com
The domestic dog represents one of the most dramatic long-term evolutionary experiments
undertaken by humans. From a large wolf-like progenitor, unparalleled diversity in …

Convergent evolution in human and domesticate adaptation to high-altitude environments

KE Witt, E Huerta-Sánchez - … Transactions of the Royal …, 2019 - royalsocietypublishing.org
Humans and their domestic animals have lived and thrived in high-altitude environments
worldwide for thousands of years. These populations have developed a number of …

Altitude adaptation: a glimpse through various lenses

TS Simonson - High altitude medicine & biology, 2015 - liebertpub.com
Abstract Simonson, Tatum S. Altitude adaptation: A glimpse through various lenses. High Alt
Med Biol 16: 125–137, 2015.—Recent availability of genome-wide data from highland …

Dog10K: an international sequencing effort to advance studies of canine domestication, phenotypes and health

EA Ostrander, GD Wang, G Larson… - National science …, 2019 - academic.oup.com
Dogs are the most phenotypically diverse mammalian species, and they possess more
known heritable disorders than any other non-human mammal. Efforts to catalog and …

[LIVRE][B] Breed predispositions to disease in dogs and cats

A Gough, A Thomas, D O'Neill - 2018 - books.google.com
Breed Predispositions to Disease in Dogs and Cats, Third Edition provides a comprehensive
exploration of current knowledge of breed predispositions based on rigorous examination of …

Whole-genome sequencing of eight goat populations for the detection of selection signatures underlying production and adaptive traits

X Wang, J Liu, G Zhou, J Guo, H Yan, Y Niu, Y Li… - Scientific reports, 2016 - nature.com
The goat (Capra hircus) is one of the first farm animals that have undergone domestication
and extensive natural and artificial selection by adapting to various environments, which in …

Long-term small population size, deleterious variation, and altitude adaptation in the Ethiopian wolf, a severely endangered canid

JA Mooney, CD Marsden, A Yohannes… - Molecular Biology …, 2023 - academic.oup.com
Ethiopian wolves, a canid species endemic to the Ethiopian Highlands, have been steadily
declining in numbers for decades. Currently, out of 35 extant species, it is now one of the …

Cross-species insights into genomic adaptations to hypoxia

ME Pamenter, JE Hall, Y Tanabe… - Frontiers in Genetics, 2020 - frontiersin.org
Over millions of years, vertebrate species populated vast environments spanning the globe.
Among the most challenging habitats encountered were those with limited availability of …

Genome-wide analysis reveals adaptation to high altitudes in Tibetan sheep

C Wei, H Wang, G Liu, F Zhao, JW Kijas, Y Ma, J Lu… - Scientific reports, 2016 - nature.com
Tibetan sheep have lived on the Tibetan Plateau for thousands of years; however, the
process and consequences of adaptation to this extreme environment have not been …

Hypoxia Inducible Factor (HIF) transcription factor family expansion, diversification, divergence and selection in eukaryotes

AM Graham, JS Presnell - PloS one, 2017 - journals.plos.org
Hypoxia inducible factor (HIF) transcription factors are crucial for regulating a variety of
cellular activities in response to oxygen stress (hypoxia). In this study, we determine the …