Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

Osteoarthritis (OA) is a chronic disease and the most common orthopedic disorder. A vast
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …

Objective To estimate systematic and anatomic site–specific age‐standardized prevalence
rates (ASRs) and analyze the secular trends of osteoarthritis (OA) at global, regional, and …

Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

Background Osteoarthritis is the most common form of arthritis in adults, characterised by
chronic pain and loss of mobility. Osteoarthritis most frequently occurs after age 40 years …

Knee osteoarthritis (KOA) is a common chronic articular disease worldwide. It is also the
most common form of OA and is characterized by high morbidity and disability rates. With the …

Objective To evaluate the trends and cross-country inequalities of global osteoarthritis (OA)
burden over the last 30 years, and further predicted its changes to 2035. Methods The …

Understanding of the basis of osteoarthritis (OA) has seen some interesting advancements
in recent years. It has been observed that cartilage degeneration is preceded by …

Macrophages are influential members of the innate immune system that can be reversibly
polarized by different microenvironment signals. Cell polarization leads to a wide range of …

In spite of the considerable achievements in the field of regenerative medicine in the past
several decades, osteochondral defect regeneration remains a challenging issue among …