Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Skeletal muscle atrophy is the consequence of protein degradation exceeding protein
synthesis because of disease, aging, and physical inactivity. Patients with skeletal muscle …

The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …

Background and Purpose Increasing evidence suggests systemic inflammation‐caused
skeletal muscle atrophy as a major clinical feature of cachexia. Triptolide obtained from …

Myocardial infarction (MI)-induced heart failure (HF) is commonly accompanied with
profound effects on skeletal muscle. With the process of MI-induced HF, perturbations in …

Muscle and bone interact via physical forces and secreted osteokines and myokines.
Physical forces are generated through gravity, locomotion, exercise, and external devices …

Estrogens (estradiol, estriol, and estrone) are important hormones that directly and indirectly
regulate the metabolism and function of bone and skeletal muscle via estrogen receptors …

Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Sarcopenic obesity (SO) is a condition characterized by the occurrence of both sarcopenia
and obesity and imposes a heavy burden on the health of the elderly. Controversies and …

Skeletal muscle fibres are multinucleated cells that contain postmitotic nuclei (ie they are no
longer able to divide) and perform muscle contraction. They are formed by fusion of muscle …