Omicron variant of SARS‐CoV‐2: genomics, transmissibility, and responses to current COVID‐19 vaccines

Y Araf, F Akter, Y Tang, R Fatemi… - Journal of medical …, 2022 - Wiley Online Library
Currently, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has spread
worldwide as an Omicron variant. This variant is a heavily mutated virus and designated as …

Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

Emergence of SARS-CoV-2 Omicron (B. 1.1. 529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic

R Khandia, S Singhal, T Alqahtani, MA Kamal… - Environmental …, 2022 - Elsevier
Since the appearance in the late of December 2019, SARS-CoV-2 is rapidly evolving and
mutating continuously, giving rise to various variants with variable degrees of infectivity and …

Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

J Ou, W Lan, X Wu, T Zhao, B Duan, P Yang… - … and Targeted Therapy, 2022 - nature.com
The current pandemic of COVID-19 is fueled by more infectious emergent Omicron variants.
Ongoing concerns of emergent variants include possible recombinants, as genome …

[HTML][HTML] Global emerging Omicron variant of SARS-CoV-2: Impacts, challenges and strategies

K Dhama, F Nainu, A Frediansyah, MI Yatoo… - Journal of infection and …, 2023 - Elsevier
Newly emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
are continuously posing high global public health concerns and panic resulting in waves of …

Comparison of patients infected with Delta versus Omicron COVID-19 variants presenting to Paris emergency departments: a retrospective cohort study

D Bouzid, B Visseaux, C Kassasseya… - Annals of internal …, 2022 - acpjournals.org
Background: At the end of 2021, the B. 1.1. 529 SARS-CoV-2 variant (Omicron) wave
superseded the B. 1.617. 2 variant (Delta) wave. Objective: To compare baseline …

Cryo-EM structure of a SARS-CoV-2 omicron spike protein ectodomain

G Ye, B Liu, F Li - Nature communications, 2022 - nature.com
The omicron variant of SARS-CoV-2 has been spreading rapidly across the globe. The virus-
surface spike protein plays a critical role in the cell entry and immune evasion of SARS-CoV …

[HTML][HTML] Omicron variant (B. 1.1. 529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?

M Dhawan, ARA Saied, S Mitra, FA Alhumaydhi… - Biomedicine & …, 2022 - Elsevier
Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …

Essential role of TMPRSS2 in SARS-CoV-2 infection in murine airways

N Iwata-Yoshikawa, M Kakizaki, N Shiwa-Sudo… - Nature …, 2022 - nature.com
In cultured cells, SARS-CoV-2 infects cells via multiple pathways using different host
proteases. Recent studies have shown that the furin and TMPRSS2 (furin/TMPRSS2) …

New coronavirus variants are creating more challenges to global healthcare system: a brief report on the current knowledge

S Islam, T Islam, MR Islam - Clinical pathology, 2022 - journals.sagepub.com
The coronavirus is naturally mutating over time and producing new variants. Some of them
are more contagious and destructive than previous strains. Also, some variants are capable …