Sodium-iodide symporter and its related solute carriers in thyroid cancer
The solute carrier (SLC) family is a large group of membrane transport proteins. Their
dysfunction plays an important role in the pathogenesis of thyroid cancer. The most well …
dysfunction plays an important role in the pathogenesis of thyroid cancer. The most well …
Functional characterization of novel compound heterozygous missense SLC5A5 gene variants causing congenital dyshormonogenic hypothyroidism
Introduction The sodium/iodide symporter (NIS) mediates active iodide accumulation in the
thyroid follicular cell. Biallelic loss-of-function variants in the NIS-coding SLC5A5 gene …
thyroid follicular cell. Biallelic loss-of-function variants in the NIS-coding SLC5A5 gene …
Novel molecular ty** reveals the risk of recurrence in patients with early-stage papillary thyroid cancer
M Sun, B Zhao, T Chen, L Yao, X Li, S Hu, C Chen… - Thyroid Research, 2024 - Springer
Background Papillary thyroid cancer (PTC) is an indolent disease with a favorable prognosis
but characterized by a high recurrence rate. We aimed to improve precise stratification of …
but characterized by a high recurrence rate. We aimed to improve precise stratification of …
A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer
MG Lechner, GA Brent - Clinical Cancer Research, 2024 - AACR
Advanced differentiated thyroid cancer that is resistant to radioactive iodine therapy may
become responsive with a unique treatment combination of chloroquine and vorinostat. This …
become responsive with a unique treatment combination of chloroquine and vorinostat. This …