Mitophagy is a highly conserved cellular process that maintains the mitochondrial quantity
by eliminating dysfunctional or superfluous mitochondria through autophagy machinery. The …

Basal autophagy plays a critical role in maintaining cellular homeostasis and genomic
integrity by degrading aged or malfunctioning organelles and damaged or misfolded …

Premature ovarian insufficiency (POI) is a major cause of female infertility due to early loss of
ovarian function. POI is a heterogeneous condition, and its molecular etiology is unclear. To …

Common variant genome-wide association studies (GWASs) have, to date, identified> 24
risk loci for Parkinson's disease (PD). To discover additional loci, we carried out a GWAS …

Many researchers, especially those new to the field, need to determine which criteria are
essential for demonstrating autophagy, either for the purposes of their own research, or in …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Exosomes derived from solid tumor cells are involved in immune suppression,
angiogenesis, and metastasis, but the role of leukemia-derived exosomes has been less …

Overcoming metabolic stress is a critical step in tumor growth. Acetyl coenzyme A (acetyl-
CoA) generated from glucose and acetate uptake is important for histone acetylation and …

In solid tumors, cancer stem cells (CSCs) or tumor-initiating cells (TICs) are often found in
hypoxic niches. Nevertheless, the influence of hypoxia on TICs is poorly understood. Using …