Flavonoids are natural plant-derived dietary bioactive compounds having a substantial
impact on human health. Morin hydrate is a bioflavonoid mainly obtained from fruits, stem …

Acrylamide (ACR) is a heat-induced carcinogen substance that is found in some foods due
to cooking or other thermal processes. The aim of present study was to assess the probable …

The Global cancer incidence and mortality data released by the World Health Organization
proposes that out of 18.1 million new cancer cases diagnosed, 9.8 million deaths occurred …

Background Organ toxicity limits the therapeutic efficacy of methotrexate (MTX), an anti-
metabolite therapeutic that is frequently used as an anti-cancer and immunosuppressive …

Although Doxorubicin (DOX) is a widespread drug used in the treatment of cancer, its
clinical use is restricted due to its common side effects. In addition, administrating DOX with …

Morin, a bioflavonoid with diverse pharmacological effects against various diseases; in most
cases morin protective effects were attributed to its detoxifying effect against reactive oxygen …

Aims Endoplasmic reticulum stress (ERS) with aberrant mitochondrial-ER contact (MERC),
mitophagy, and apoptosis are interconnected determinants in neurodegenerative diseases …

Nephrotoxicity remain a major life-threatening complication in cancer patients on cisplatin
chemotherapy. In this study, we investigated the protective effect and possible cellular …

The nucleotide‐binding oligomerization domain‐like receptor family, pyrin domain
containing 3 (NLRP3) inflammasome has a key role in the inflammatory response. We found …

Purpose This study aimed at evaluating whether morin (a natural flavonoid and a known
inhibitor of NF-κB) can sensitize ovarian cancer cells to cisplatin by decreasing the …