Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders

B Dinda, S Dinda, S DasSharma, R Banik… - European journal of …, 2017 - Elsevier
Abstract The flavonoids, baicalin (5, 6-dihydroxy-2-phenyl-4H-1-benzopyran-4-one-7-Od-β-
glucuronic acid) 1 and its aglycone, baicalein 2 are found in edible medicinal plants …

Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials

I Jantan, W Ahmad, SNA Bukhari - Frontiers in plant science, 2015 - frontiersin.org
The phagocyte–microbe interactions in the immune system is a defense mechanism but
when excessively or inappropriately deployed can harm host tissues and participate in the …

[HTML][HTML] The role of natural antioxidants in cisplatin-induced hepatotoxicity

N Abd Rashid, SAS Abd Halim, SL Teoh… - Biomedicine & …, 2021 - Elsevier
Cisplatin is a potent platinum-based anticancer drug approved by the Food Drug
Administration (FDA) in 1978. Despite its advantages against solid tumors, cisplatin confers …

Dietary polyphenols: Structures, bioavailability and protective effects against atherosclerosis

AB Santhakumar, M Battino… - Food and Chemical …, 2018 - Elsevier
Epidemiological studies have demonstrated that nutritional habits, like those based on high
consumption of fruits and vegetables, have been associated with a longer life expectancy …

Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies

GF Meresman, M Götte… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Given the disadvantages and limitations of current endometriosis therapy,
there is a progressive increase in studies focusing on plant-derived agents as a natural …

Kuijieyuan decoction improved intestinal barrier injury of ulcerative colitis by affecting TLR4-dependent PI3K/AKT/NF-κB oxidative and inflammatory signaling and gut …

B Liu, X Piao, W Niu, Q Zhang, C Ma, T Wu… - Frontiers in …, 2020 - frontiersin.org
Ethnopharmacological Relevance In Traditional Chinese medicine (TCM) theory, ulcerative
colitis (UC) is associated with damp-heat, blood stasis, and intestinal vascular ischemia …

Exploration of nitrogen-doped grape peels carbon dots for baicalin detection

X Tang, H Wang, H Yu, B Bui, W Zhang, S Wang… - Materials Today …, 2022 - Elsevier
Baicalin, a flavonoid compound extracted from the rhizome of Scutellar iae Baicalensis,
plays a vital role in improving liver function after injury, reducing liver disease and treating …

Baicalein increases cisplatin sensitivity of A549 lung adenocarcinoma cells via PI3K/Akt/NF-κB pathway

M Yu, B Qi, W **aoxiang, J Xu, X Liu - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Baicalein, a bioactive flavonoid, exhibits anti-inflammatory and anti-cancer activities.
However, few studies reported the interaction of baicalein with chemotherapeutic agents …

Flavonoids as potential phytotherapeutics to combat cytokine storm in SARS‐CoV‐2

A Gour, D Manhas, S Bag, B Gorain… - Phytotherapy …, 2021 - Wiley Online Library
Emergence of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection,
COVID‐19, has become the global panic since December 2019, which urges the global …

[HTML][HTML] A baicalin-loaded coaxial nanofiber scaffold regulated inflammation and osteoclast differentiation for vascularized bone regeneration

S **, J Gao, R Yang, C Yuan, R Wang, Q Zou, Y Zuo… - Bioactive materials, 2022 - Elsevier
We demonstrate a simple, effective and feasible method to address the shrinkage of Poly
(lactic-co-glycolic acid)(PLGA) through a core-shell structure fiber strategy. The results …