[HTML][HTML] Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment

M Zhang, W Hu, C Cai, Y Wu, J Li, S Dong - Materials Today Bio, 2022 - Elsevier
Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …

Challenges and opportunities of nanomedicines in clinical translation

C Zheng, M Li, J Ding - Bio Integration, 2021 - scienceopen.com
The clinical approval of the first nanoparticle-based drug, liposomal doxorubicin (Doxil®), for
cancer therapy in the United States in 1995 has marked the entrance of nanomedicines in …

Screening for lipid nanoparticles that modulate the immune activity of helper T cells towards enhanced antitumour activity

Y Zhu, J Ma, R Shen, J Lin, S Li, X Lu… - Nature biomedical …, 2024 - nature.com
Lipid nanoparticles (LNPs) can be designed to potentiate cancer immunotherapy by
promoting their uptake by antigen-presenting cells, stimulating the maturation of these cells …

Advanced microfluidic technologies for lipid nano-microsystems from synthesis to biological application

BG Carvalho, BT Ceccato, M Michelon, SW Han… - Pharmaceutics, 2022 - mdpi.com
Microfluidics is an emerging technology that can be employed as a powerful tool for
designing lipid nano-microsized structures for biological applications. Those lipid structures …

Metal-enriched HSP90 nanoinhibitor overcomes heat resistance in hyperthermic intraperitoneal chemotherapy used for peritoneal metastases

Q Wang, P Liu, Y Wen, K Li, B Bi, B Li, M Qiu, S Zhang… - Molecular cancer, 2023 - Springer
Clinical hyperthermic intraperitoneal chemotherapy (HIPEC) is regarded as a potential
treatment that can prolong survival of patients with peritoneal metastases after cytoreductive …

Lipid-and polymer-based nanocarrier platforms for cancer vaccine delivery

S Sunoqrot, SA Abdel Gaber, R Abujaber… - ACS Applied Bio …, 2024 - ACS Publications
Cancer immunotherapy has gained popularity in recent years in the search for effective
treatment modalities for various malignancies, particularly those that are resistant to …

Kinetically controlled polyelectrolyte complex assembly of microRNA‐peptide nanoparticles toward treating mesothelioma

CF Anderson, A Singh, T Stephens… - Advanced …, 2024 - Wiley Online Library
Broad size distributions and poor long‐term colloidal stability of microRNA‐carrying
nanoparticles, especially those formed by polyelectrolyte complexation, represent major …

High‐Precision Synthesis of RNA‐Loaded Lipid Nanoparticles for Biomedical Applications

H Seo, L Jeon, J Kwon, H Lee - Advanced Healthcare …, 2023 - Wiley Online Library
The recent development of RNA‐based therapeutics in delivering nucleic acids for gene
editing and regulating protein translation has led to the effective treatment of various …

mRNA delivery: challenges and advances through polymeric soft nanoparticles

S Yousefi Adlsadabad, JW Hanrahan… - International Journal of …, 2024 - mdpi.com
Single-stranded messenger ribonucleic acid (mRNA) plays a pivotal role in transferring
genetic information, and tremendous effort has been devoted over the years to utilize its …

Sustained release systems for delivery of therapeutic peptide/protein

T Nie, W Wang, X Liu, Y Wang, K Li, X Song… - …, 2021 - ACS Publications
Peptide/protein therapeutics have been significantly applied in the clinical treatment of
various diseases such as cancer, diabetes, etc. owing to their high biocompatibility …