The overuse of antibiotics has led to the emergence of a large number of antibiotic-resistant
genes in bacteria, and increasing evidence indicates that a fungicide with an antibacterial …

For more than 50 years dequalinium chloride has been used successfully as an antiseptic
drug and disinfectant, particularly for clinical purposes. Given the success of dequalinium …

A novel class of orally active antimalarial 3, 5-diaryl-2-aminopyridines has been identified
from phenotypic whole cell high-throughput screening of a commercially available SoftFocus …

Naturally occurring polyamines (PAs) play a pivotal role in the life of all organisms from
bacteria to man. The human PAs putrescine, spermidine, and spermine are fundamental for …

A series of novel ferrocene-pyrazole derivatives containing nitric oxide donors as COX-2
inhibitors for cancer therapy were designed, synthesized and biologically evaluated. Among …

Quaternary ammonium salts (QASs) have been widely used for disinfection purposes
because of their low price, high efficacy and low human toxicity for decades. However …

Since the discovery of antimicrobial agents, the misuse of antibiotics has led to the
emergence of bacterial strains resistant to both antibiotics and common disinfectants like …

Polytopic ligands have become ubiquitous in coordination chemistry because they grant
access to a variety of mono‐and polynuclear complexes of transition metals as well as rare …

The organocatalytic controlled/living ring-opening polymerization (ROP) of monofunctional
cyclotrisiloxanes using water or silanols as initiators, guanidines as catalysts, and …

Guanidines to begin with, were thought of being harmful substances associated with
medical ailment. With the advent of World War I and the impact it left on the populations at …