NMR spectroscopy for metabolomics research

AH Emwas, R Roy, RT McKay, L Tenori, E Saccenti… - Metabolites, 2019 - mdpi.com
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

Deuterium‐and tritium‐labelled compounds: applications in the life sciences

J Atzrodt, V Derdau, WJ Kerr… - Angewandte chemie …, 2018 - Wiley Online Library
Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …

A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms

H Tsugawa, R Nakabayashi, T Mori, Y Yamada… - Nature …, 2019 - nature.com
We report a computational approach (implemented in MS-DIAL 3.0; http://prime. psc. riken.
jp/) for metabolite structure characterization using fully 13C-labeled and non-labeled plants …

[HTML][HTML] Secondary metabolism in Trichoderma–chemistry meets genomics

S Zeilinger, S Gruber, R Bansal, PK Mukherjee - Fungal biology reviews, 2016 - Elsevier
Species of the genus Trichoderma inhabit diverse environments and undergo a variety of
interactions with different other organisms. Mycoparasitic Trichoderma species are …

Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield

T Isah, S Umar, A Mujib, MP Sharma… - Plant Cell, Tissue and …, 2018 - Springer
Biotechnology is playing a vital alternative role in the production of pharmaceutical plant
secondary metabolites to support industrial production and mitigate over-exploitation of …

Advanced analytical and informatic strategies for metabolite annotation in untargeted metabolomics

Y Cai, Z Zhou, ZJ Zhu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Liquid chromatography–mass spectrometry (LC–MS)-based untargeted metabolomics is
constantly challenged by large-scale and unambiguous metabolite annotation in complex …

Metabolomics in infectious diseases and drug discovery

V Tounta, Y Liu, A Cheyne, G Larrouy-Maumus - Molecular omics, 2021 - pubs.rsc.org
Metabolomics has emerged as an invaluable tool that can be used along with genomics,
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …

Analytical methods for detection of plant metabolomes changes in response to biotic and abiotic stresses

A Piasecka, P Kachlicki, M Stobiecki - International journal of molecular …, 2019 - mdpi.com
Abiotic and biotic stresses are the main reasons of substantial crop yield losses worldwide.
Research devoted to reveal mechanisms of plant reactions during their interactions with the …

Metabolomics as an emerging tool to study plant–microbe interactions

S Gupta, M Schillaci, U Roessner - Emerging Topics in Life …, 2022 - portlandpress.com
In natural environments, interaction between plant roots and microorganisms are common.
These interactions between microbial species and plants inhabited by them are being …

Chain elongators, friends, and foes

P Candry, R Ganigué - Current Opinion in Biotechnology, 2021 - Elsevier
Highlights•A meta-analysis of chain elongation microbiomes shows community
divergence.•Key microbiome members are often not classified or characterized.•Isolated …