GTRD: an integrated view of transcription regulation
Abstract The Gene Transcription Regulation Database (GTRD; http://gtrd. biouml. org/)
contains uniformly annotated and processed NGS data related to gene transcription …
contains uniformly annotated and processed NGS data related to gene transcription …
The NHGRI-EBI GWAS Catalog: knowledgebase and deposition resource
E Sollis, A Mosaku, A Abid, A Buniello… - Nucleic acids …, 2023 - academic.oup.com
Abstract The NHGRI-EBI GWAS Catalog (www. ebi. ac. uk/gwas) is a FAIR knowledgebase
providing detailed, structured, standardised and interoperable genome-wide association …
providing detailed, structured, standardised and interoperable genome-wide association …
Prediction of Clinical Trials Outcomes Based on Target Choice and Clinical Trial Design with Multi‐Modal Artificial Intelligence
Drug discovery and development is a notoriously risky process with high failure rates at
every stage, including disease modeling, target discovery, hit discovery, lead optimization …
every stage, including disease modeling, target discovery, hit discovery, lead optimization …
The GTEx Consortium atlas of genetic regulatory effects across human tissues
GTEx Consortium - Science, 2020 - science.org
The Genotype-Tissue Expression (GTEx) project was established to characterize genetic
effects on the transcriptome across human tissues and to link these regulatory mechanisms …
effects on the transcriptome across human tissues and to link these regulatory mechanisms …
The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
A Buniello, JAL MacArthur, M Cerezo… - Nucleic acids …, 2019 - academic.oup.com
The GWAS Catalog delivers a high-quality curated collection of all published genome-wide
association studies enabling investigations to identify causal variants, understand disease …
association studies enabling investigations to identify causal variants, understand disease …
ChEMBL: towards direct deposition of bioassay data
ChEMBL is a large, open-access bioactivity database (https://www. ebi. ac. uk/chembl),
previously described in the 2012, 2014 and 2017 Nucleic Acids Research Database Issues …
previously described in the 2012, 2014 and 2017 Nucleic Acids Research Database Issues …
The next-generation Open Targets Platform: reimagined, redesigned, rebuilt
Abstract The Open Targets Platform (https://platform. opentargets. org/) is an open source
resource to systematically assist drug target identification and prioritisation using publicly …
resource to systematically assist drug target identification and prioritisation using publicly …
PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations
MA Kamat, JA Blackshaw, R Young, P Surendran… - …, 2019 - academic.oup.com
PhenoScanner is a curated database of publicly available results from large-scale genetic
association studies in humans. This online tool facilitates 'phenome scans', where genetic …
association studies in humans. This online tool facilitates 'phenome scans', where genetic …
The BioGRID interaction database: 2019 update
R Oughtred, C Stark, BJ Breitkreutz, J Rust… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Biological General Repository for Interaction Datasets (BioGRID:
https://thebiogrid. org) is an open access database dedicated to the curation and archival …
https://thebiogrid. org) is an open access database dedicated to the curation and archival …
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
J MacArthur, E Bowler, M Cerezo, L Gil… - Nucleic acids …, 2017 - academic.oup.com
Abstract The NHGRI-EBI GWAS Catalog has provided data from published genome-wide
association studies since 2008. In 2015, the database was redesigned and relocated to …
association studies since 2008. In 2015, the database was redesigned and relocated to …