Association of TERT (rs2736098 and rs2736100) genetic variants with elevated risk of hepatocellular carcinoma: a retrospective case–control study
Hepatocellular carcinoma (HCC) is an inflammatory problematic issue with higher mortality
among different ethnic populations. The telomerase reverse transcriptase (TERT) gene has …
among different ethnic populations. The telomerase reverse transcriptase (TERT) gene has …
The blockage signal for PD-L1/CD274 gene variants and their potential impact on lung carcinoma susceptibility
Background The programmed death-ligand 1 (PD-L1/CD274) gene plays a key function in
suppressing anti-tumor immunity through binding to its receptor PD-1 on stimulated T …
suppressing anti-tumor immunity through binding to its receptor PD-1 on stimulated T …
Association of CCND1 (c. 723G> A, rs9344) variant with elevated risk of breast carcinoma: a retrospective case–control study
MA El-Eshmawy, HE Shahin, NS El-Beltagy… - Molecular Biology …, 2023 - Springer
Background The prevalence rate of breast carcinoma (BC) among multiple ethnic
populations required more explanations to understand the pathogenesis mechanisms for …
populations required more explanations to understand the pathogenesis mechanisms for …
Pharmacogenetic insights into ABCB1, ABCC2, CYP1A2, and CYP2B6 variants with epilepsy susceptibility among Egyptian Children: A retrospective case-control …
ZR Attia, ME Labib, AK Kelany, RM Alnefaie… - International …, 2024 - Elsevier
Background Pediatric epilepsy is a complicated neuropsychiatric disorder that is
characterized by recurrent seizures and unusual synchronized electrical activities within …
characterized by recurrent seizures and unusual synchronized electrical activities within …
Polymorphisms of the sodium voltage-gated channel, alpha subunit 1 (SCN1A -A3184G) gene among children with non-lesional epilepsy: a case-control study
E Ghazala, DA Shahin, Y Wahba - Italian Journal of Pediatrics, 2022 - Springer
Background Mutations in the neuronal sodium voltage-gated channel, alpha subunit 1
(SCN1A) gene have been associated with epilepsy. We investigated the SCN1A-A3184G …
(SCN1A) gene have been associated with epilepsy. We investigated the SCN1A-A3184G …
[HTML][HTML] GEMIN4 Variants: Risk Profiling, Bioinformatics, and Dynamic Simulations Uncover Susceptibility to Bladder Carcinoma
Background The relationship between GEMIN4 genetic variants and cancer, especially
bladder carcinoma (BLCA), has been explored without conclusive results. This study aims to …
bladder carcinoma (BLCA), has been explored without conclusive results. This study aims to …
Potential Impact of SOD2 (rs4880; p. Val16Ala) Variant with the Susceptibility for Childhood Bronchial Asthma
Oxidative stress is a sophisticated situation that orignates from the accumulation of reactive
free radicals within cellular compartments. The antioxidant mechanism of the MnSOD …
free radicals within cellular compartments. The antioxidant mechanism of the MnSOD …
Genetic Variants of AGO1* rs595961 and AGO2* rs4961280 with Susceptibility to Bladder Carcinoma
The microRNA (miRNA) biogenesis mechanism remains elusive, yet various genetic
variants may play a role in predicting the biological function of this machinery system and its …
variants may play a role in predicting the biological function of this machinery system and its …
The efficacy of cyclophosphamide combined with prednisone in membranous nephropathy patients with different cytochrome P450 2B6 gene polymorphisms and …
M Zhang, Y Lv, H Liu - Drug Design, Development and Therapy, 2023 - Taylor & Francis
Objective To investigate the efficacy of cyclophosphamide combined with prednisone in
membranous nephropathy (MN) patients with different cytochrome P450 (CYP) 2B6 gene …
membranous nephropathy (MN) patients with different cytochrome P450 (CYP) 2B6 gene …
Association of the Role MTHFR 677C> T and 1298A> C polymorphisms variants as the risk factor with human male infertility.
The aim of the current study was to investigate the association between male infertility and
the MTHFR (677C> T; 1298A> C), polymorphisms in a Egyptian population. We conducted a …
the MTHFR (677C> T; 1298A> C), polymorphisms in a Egyptian population. We conducted a …