Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous
group of autoimmune disorders with varying clinical manifestations, treatment responses …

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A human gut-on-a-chip microdevice was used to coculture multiple commensal microbes in
contact with living human intestinal epithelial cells for more than a week in vitro and to …

Antimicrobial peptides (AMPs) have been considered as potential therapeutic sources of
future antibiotics because of their broad-spectrum activities and different mechanisms of …

Abstract Treatment of inflammatory diseases today is largely based on interrupting the
synthesis or action of mediators that drive the host's response to injury. Non-steroidal anti …

In recent years nanotechnology has revolutionized the healthcare strategies and envisioned
to have a tremendous impact to offer better health facilities. In this context, medical …

Obesity and its related health complications is a major problem worldwide. Hypothalamus
and their signalling molecules play a critical role in the intervening and coordination with …

Abstract The melanocortin-4 receptor (MC4R) was cloned in 1993 by degenerate PCR;
however, its function was unknown. Subsequent studies suggest that the MC4R might be …

Microglial cells are responsible for immune surveillance within the CNS. They respond to
noxious stimuli by releasing inflammatory mediators and mounting an effective inflammatory …

Skin pigmentation is due to the accumulation of two types of melanin granules in the
keratinocytes. Besides being the most potent blocker of ultraviolet radiation, the role of …