Bactericidal Activity to Escherichia coli: Different Modes of Action of Two 24-Mer Peptides SAAP-148 and OP-145, Both Derived from Human Cathelicidine LL-37

A Ön, D Vejzovic, J Jennings, L Parigger… - Antibiotics, 2023 - mdpi.com
OP-145 and SAAP-148, two 24-mer antimicrobial peptides derived from human cathelicidin
LL-37, exhibit killing efficacy against both Gram-positive and Gram-negative bacteria at …

The influence of the pectin structure on the properties of hydrogel dressings doped with octenidine-containing antiseptic

M Fiedot, A Junka, M Brożyna, J Cybulska… - Carbohydrate …, 2024 - Elsevier
This article presents a method for producing hydrogel dressings using high methylated
pectin from apples or citrus, doped with the antiseptic agent, octenidine dihydrochloride …

Combinatorial Screening of Cationic Lipidoids Reveals How Molecular Conformation Affects Membrane-Targeting Antimicrobial Activity

J Jennings, D Ašćerić, EF Semeraro… - … Applied Materials & …, 2023 - ACS Publications
The search for next-generation antibacterial compounds that overcome the development of
resistance can be facilitated by identifying how to target the cell membrane of bacteria …

Ethanolic cashew leaf extract: Antimicrobial activity, mode of action, and retardation of spoilage bacteria in refrigerated Nile tilapia slices

P Sinlapapanya, P Sumpavapol, N Nirmal, B Zhang… - Foods, 2022 - mdpi.com
Phenolic compounds from cashew (Anacardium occidentale L.) leaves were extracted using
ethanol with the aid of ultrasonication. Three independent variables, including ultrasound …

[HTML][HTML] Designing Antibacterial-Based Quaternary Ammonium Coatings (Surfaces) or Films for Biomedical Applications: Recent Advances

GC Lainioti, D Druvari - International Journal of Molecular Sciences, 2024 - mdpi.com
Antibacterial coatings based on quaternary ammonium compounds (QACs) have been
widely investigated in controlled release applications. Quaternary ammonium compounds …

Clinical Evidence for the Use of Octenidine Dihydrochloride to Prevent Healthcare-Associated Infections and Decrease Staphylococcus aureus Carriage or …

R Köck, L Denkel, AT Feßler, R Eicker, A Mellmann… - Pathogens, 2023 - mdpi.com
Background: The antiseptic agent octenidine dihydrochloride (OCT) is used for skin
preparation, for Staphylococcus aureus decolonization, and within bundles for the …

Structure–Activity Relationships of Cationic Lipidoids against Escherichia coli

J Jennings, D Ašćerić, N Malanovic, G Pabst - Antibiotics, 2023 - mdpi.com
Membrane-active molecules provide a promising strategy to target and kill pathogenic
bacteria. Understanding how specific molecular features drive interactions with membrane …

In vitro long-term exposure to chlorhexidine or triclosan induces cross-resistance against azoles in Nakaseomyces glabratus

K Spettel, D Bumberger, R Kriz, S Frank, M Loy… - … Resistance & Infection …, 2025 - Springer
Background Topical antiseptics are crucial for preventing infections and reducing
transmission of pathogens. However, commonly used antiseptic agents have been reported …

Efficiency of octenidine dihydrochloride alcohol combination compared to ethanol based skin antiseptics for preoperative skin preparation in dogs

F Eigner, S Keller, S Schmitt, S Corti, MC Nolff - Plos one, 2023 - journals.plos.org
Objective To quantify the bacterial burden after skin disinfection using an alcohol octenidine
dihydrochloride combination (Octenisept®) compared to an 74.1% ethanol 10% 2-propanol …

[HTML][HTML] New Insights Regarding the Use of Relevant Synthetic Compounds in Dentistry

SI Dumitrel, A Matichescu, S Dinu, R Buzatu… - Molecules, 2024 - mdpi.com
Worldwide, synthetic compounds are used for both in-office and at-home dental care. They
are a valuable resource for both prophylactic and curative treatments for various dental …