Drug repurposing has become an effective approach to drug discovery, as it offers a new
way to explore drugs. Based on the Science Citation Index Expanded (SCI-E) and Social …

Abstract Topoisomerase II (TOP-2) is a promising molecular target for cancer therapy.
Numerous antibiotics could interact with biologically relevant macromolecules and provoke …

Biological resources (cells, tissues, bodily fluids or biomolecules) are considered essential
raw material for the advancement of health-related biotechnology, for research and …

Accurately identifying novel indications for drugs is crucial in drug research and discovery.
Traditional drug discovery is costly and time-consuming. Computational drug repositioning …

With the rapid development of high-throughput genomic technologies and the accumulation
of genome-wide datasets for human disease, it has been shown that using only …

Background Drug repositioning is the process of identifying new targets for known drugs. It
can be used to overcome problems associated with traditional drug discovery by adapting …

Background It often takes more than 10 years and costs more than 1 billion dollars to
develop a new drug for a particular disease and bring it to the market. Drug repositioning …

Drug repurposing has become a widely used strategy to accelerate the process of finding
treatments. While classical de novo drug development involves high costs, risks, and time …

Background Develo** novel uses of approved drugs, called drug repositioning, can
reduce costs and times in traditional drug development. Network-based approaches have …

Traditional drug discovery methods focus on optimizing the efficacy of a drug against a
single biological target of interest for a specific disease. However, evidence supports the …