Pseudomonas aeruginosa, a ubiquitous opportunistic and nosocomial biofilm-forming
pathogen with complex, interconnected and hierarchical nature of QS systems (Las, Rhl …

The grand challenge in structure-based drug design is achieving accurate prediction of
binding free energies. Molecular dynamics (MD) simulations enable modeling of …

Biofilms are aggregates of microorganisms anchored to a surface and embedded in a self-
produced matrix of extracellular polymeric substances and have been associated with 80 …

The recent study investigated the in vitro anti-diabetic impact of the crude extract (MeOH)
and subfractions ethyl acetate (EtOAc); chloroform; n-butanol; n-hexane; and aqueous …

In Pseudomonas aeruginosa (P. aeruginosa), transcription factors (TFs) are important
mediators in the genetic regulation of adaptability and pathogenicity to respond to multiple …

The rapid proliferation and colonization of probiotics in the intestines are essential for
human health. Quorum sensing (QS) is a communication mechanism among bacteria, which …

Phyllanthus emblica is a traditional medicinal plant that is endowed with curative properties
including anti-bacterial, anti-fungal, anti-viral, and analgesic properties. Bacteria make use …

The aim of the present study is to investigate the effective antimicrobial and antibiofilm
properties of fenchone, a biologically active bicyclic monoterpene, against infections caused …

Background Heterocyclic analogs of curcumin have a wide range of therapeutic potential
and the ability to control the activity of a variety of metabolic enzymes. Methods 1H-NMR and …

Bacteriocins are gaining immense importance in therapeutics since they show significant
antibacterial potential. This study reports the bacteriocin KAE01 from Enterococcus faecium …