Neurotoxicity of methamphetamine: Main effects and mechanisms

S Jayanthi, AP Daiwile, JL Cadet - Experimental neurology, 2021 - Elsevier
Methamphetamine (METH) is an illicit psychostimulant that is abused throughout the world.
METH addiction is also a major public health concern and the abuse of large doses of the …

Methamphetamine toxicity and messengers of death

IN Krasnova, JL Cadet - Brain research reviews, 2009 - Elsevier
Methamphetamine (METH) is an illicit psychostimulant that is widely abused in the world.
Several lines of evidence suggest that chronic METH abuse leads to neurodegenerative …

Amphetamine toxicities: classical and emerging mechanisms

BK Yamamoto, A Moszczynska… - Annals of the New York …, 2010 - Wiley Online Library
The drugs of abuse, methamphetamine and MDMA, produce long‐term decreases in
markers of biogenic amine neurotransmission. These decreases have been traditionally …

Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

T Cunha-Oliveira, AC Rego, CR Oliveira - Brain research reviews, 2008 - Elsevier
Substance abuse and addiction are the most costly of all the neuropsychiatric disorders. In
the last decades, much progress has been achieved in understanding the effects of the …

The ubiquitin-proteasome system and learning-dependent synaptic plasticity–A 10 year update

MB Patrick, N Omar, CT Werner, S Mitra… - … & Biobehavioral Reviews, 2023 - Elsevier
Over 25 years ago, a seminal paper demonstrated that the ubiquitin-proteasome system
(UPS) was involved in activity-dependent synaptic plasticity. Interest in this topic began to …

Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors

EJ Shin, DK Dang, TV Tran, HQ Tran, JH Jeong… - Archives of Pharmacal …, 2017 - Springer
Clinical and preclinical studies have indicated that chronic methamphetamine (MA) use is
associated with extensive neurodegeneration, psychosis, and cognitive impairment …

[HTML][HTML] Current and emerging treatments for methamphetamine use disorder

A Moszczynska - Current neuropharmacology, 2021 - ncbi.nlm.nih.gov
Almost two decades have passed since the last methamphetamine (METH) abuse epidemic.
In recent years, METH abuse in the United States has been rapidly increasing and is …

Role of mitochondria in methamphetamine-induced dopaminergic neurotoxicity: involvement in oxidative stress, neuroinflammation, and pro-apoptosis—a review

EJ Shin, HQ Tran, PT Nguyen, JH Jeong, SY Nah… - Neurochemical …, 2018 - Springer
Abstract Methamphetamine (MA), an amphetamine-type psychostimulant, is associated with
dopaminergic toxicity and has a high abuse potential. Numerous in vivo and in vitro studies …

Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse

R Perfeito, T Cunha-Oliveira, AC Rego - Free Radical Biology and …, 2012 - Elsevier
Parkinson disease (PD) is a chronic and progressive neurological disease associated with a
loss of dopaminergic neurons. In most cases the disease is sporadic but genetically …

Psychoactive drugs—from chemical structure to oxidative stress related to dopaminergic neurotransmission. A review

G Jîtcă, BE Ősz, A Tero-Vescan, CE Vari - Antioxidants, 2021 - mdpi.com
Nowadays, more and more young people want to experience illegal, psychoactive
substances, without knowing the risks of exposure. Besides affecting social life …