Modeling of the HIV-1 life cycle in productively infected cells to predict novel therapeutic targets
O Shcherbatova, D Grebennikov, I Sazonov… - Pathogens, 2020 - mdpi.com
There are many studies that model the within-host population dynamics of Human
Immunodeficiency Virus Type 1 (HIV-1) infection. However, the within-infected-cell …
Immunodeficiency Virus Type 1 (HIV-1) infection. However, the within-infected-cell …
Global dynamics of an age–space structured hiv/aids model with viral load-dependent infection and conversion rates
P Wu, Z Feng, X Zhang - Journal of Computational and Applied …, 2022 - Elsevier
Distinguished from the existing HIV/AIDS epidemic models, we formulate a model by
considering three-age-structured, spacial diffusion, viral load-dependent infection and …
considering three-age-structured, spacial diffusion, viral load-dependent infection and …
Markov chain-based stochastic modelling of HIV-1 life cycle in a CD4 T cell
Replication of Human Immunodeficiency Virus type 1 (HIV) in infected CD4+ T cells
represents a key driver of HIV infection. The HIV life cycle is characterised by the …
represents a key driver of HIV infection. The HIV life cycle is characterised by the …
Modelling the dynamics of virus infection and immune response in space and time
Spreading of viral infection in the tissues such as lymph nodes or spleen depends on virus
multiplication in the host cells, their transport and on the immune response. Reaction …
multiplication in the host cells, their transport and on the immune response. Reaction …
Dynamical analysis and optimal control of an age-since infection HIV model at individuals and population levels
P Wu, Z He, A Khan - Applied Mathematical Modelling, 2022 - Elsevier
To study the impact of HIV infection at the individual level on the transmission of HIV/AIDS at
the population level, in this paper, we formulate a multi-scale HIV model coupled with a two …
the population level, in this paper, we formulate a multi-scale HIV model coupled with a two …
Mathematical modeling reveals that the administration of EGF can promote the elimination of lymph node metastases by PD-1/PD-L1 blockade
In the advanced stages of cancers like melanoma, some of the malignant cells leave the
primary tumor and infiltrate the neighboring lymph nodes (LNs). The interaction between …
primary tumor and infiltrate the neighboring lymph nodes (LNs). The interaction between …
Mechanisms for Cell-to-cell and Cell-free Spread of HIV-1 in Cellular Automata Models
Several discrete simulation models have been created to study the spread of human
immunodeficiency virus type 1 (HIV-1) within a human body. This is motivated both by the …
immunodeficiency virus type 1 (HIV-1) within a human body. This is motivated both by the …
Modelling stochastic and deterministic behaviours in virus infection dynamics
Many human infections with viruses such as human immunodeficiency virus type 1 (HIV--1)
are characterized by low numbers of founder viruses for which the random effects and …
are characterized by low numbers of founder viruses for which the random effects and …
Mathematical immunology: from phenomenological to multiphysics modelling
Mathematical immunology is the branch of mathematics dealing with the application of
mathematical methods and computational algorithms to explore the structure, dynamics …
mathematical methods and computational algorithms to explore the structure, dynamics …
Building a model and assessing the level of morbidity during the epidemic
A Kubegenova, A Gumarova… - … on Information and …, 2023 - ieeexplore.ieee.org
The article discusses the effectiveness, methods, and mathematical models of measures to
control the spread of the human immunodeficiency virus (HIV) in Kazakhstan. Data were …
control the spread of the human immunodeficiency virus (HIV) in Kazakhstan. Data were …