Epilepsy is well-recognized as a disorder of brain networks. There is a growing body of
research to identify critical nodes within dynamic epileptic networks with the aim to target …

Globally, as populations age there will be challenges and opportunities to deliver optimal
health care to senior citizens. Epilepsy, a condition characterised by spontaneous recurrent …

With advances in healthcare and an ageing population, the number of older adults with
epilepsy is set to rise substantially across the world. In developed countries the highest …

Epilepsy is a chronic disease that affects millions of people worldwide. Antiepileptic drugs
(AEDs) are used to control seizures. Even though parts of their mechanisms of action are …

This manuscript is the second part of a two-part description of the current status of
understanding of the network function of the brain in health and disease. We start with the …

Functional magnetic resonance imaging (fMRI) is increasingly used for preoperative
counseling and planning, and intraoperative guidance for tumor resection in the eloquent …

Objective In patients with epilepsy, seizure relapse and behavioral impairments can be
observed despite the absence of interictal epileptiform discharges (IED s). Therefore, the …

Drug-resistant focal epilepsy is a large-scale brain networks disorder characterized by
altered spatiotemporal patterns of functional connectivity (FC), even during interictal resting …

Cognitive impairment is a common comorbidity of epilepsy and adversely impacts people
with both frontal lobe (FLE) and temporal lobe (TLE) epilepsy. While its neural substrates …

Human neuroimaging has had a major impact on the biological understanding of epilepsy
and the relationship between pathophysiology, seizure management, and outcomes. This …