Respiratory rate is a fundamental vital sign that is sensitive to different pathological
conditions (eg, adverse cardiac events, pneumonia, and clinical deterioration) and stressors …

The American Thoracic Society/European Respiratory Society jointly created a Task Force
on “Outcomes for COPD pharmacological trials: from lung function to biomarkers” to inform …

Background A novel approach to estimate the severity of COPD exacerbation and predict its
outcome is the use of biomarkers. We assessed circulating levels of copeptin, the precursor …

Rationale: Much of the total disease burden and cost of chronic obstructive pulmonary
disease (COPD) is associated with acute exacerbations of COPD (AECOPD). Serum …

The systemic manifestations of chronic obstructive pulmonary disease (COPD)
exacerbations are recognized, but our understanding of their etiology and importance is …

Rationale: Small studies have suggested that inhaled corticosteroids can suppress systemic
inflammation in chronic obstructive pulmonary disease (COPD). Objectives: To determine …

Respiratory rate (RR) is an often underestimated and underreported vital sign with
tremendous clinical value. As a predictor of cardiopulmonary arrest, chronic obstructive …

Background The use of telehealth technologies to remotely monitor patients suffering
chronic diseases may enable preemptive treatment of worsening health conditions before a …

Background Respiratory frequency increases during exacerbations of COPD (ECOPD). We
hypothesized that this increase can be detected at home before ECOPD hospitalization …

Background There is a paucity of surrogate lung-specific biological markers that can be
used to track disease progression and predict clinical outcomes in chronic obstructive …