Accessing activity and viscoelastic properties of artificial and living systems from passive measurement

TM Muenker, G Knotz, M Krüger, T Betz - Nature Materials, 2024 - nature.com
Living systems are complex dynamic entities that operate far from thermodynamic
equilibrium. Their active, non-equilibrium behaviour requires energy to drive cellular …

Optical trap** of a single protein

Y Pang, R Gordon - Nano letters, 2012 - ACS Publications
We experimentally demonstrate the optical trap** of a single bovine serum albumin (BSA)
molecule that has a hydrodynamic radius of 3.4 nm, using a double-nanohole in an Au film …

Line optical tweezers as controllable micromachines: techniques and emerging trends

Y Shen, DA Weitz, NR Forde, M Shayegan - Soft Matter, 2022 - pubs.rsc.org
In the past three decades, the technology of optical tweezers has made significant
contributions in various scientific areas, including optics, photonics, and nanosciences …

Comparative study of methods to calibrate the stiffness of a single-beam gradient-force optical tweezers over various laser trap** powers

M Sarshar, WT Wong, B Anvari - Journal of biomedical optics, 2014 - spiedigitallibrary.org
Optical tweezers have become an important instrument in force measurements associated
with various physical, biological, and biophysical phenomena. Quantitative use of optical …

Quantitative guidelines for force calibration through spectral analysis of magnetic tweezers data

AJW Te Velthuis, JWJ Kerssemakers, J Lipfert… - Biophysical journal, 2010 - cell.com
Single-molecule techniques are powerful tools that can be used to study the kinetics and
mechanics of a variety of enzymes and their complexes. Force spectroscopy, for example …

Three-dimensional optical trap** of a plasmonic nanoparticle using low numerical aperture optical tweezers

O Brzobohatý, M Šiler, J Trojek, L Chvátal, V Karásek… - Scientific reports, 2015 - nature.com
It was previously believed that larger metal nanoparticles behave as tiny mirrors that are
pushed by the light beam radiative force along the direction of beam propagation, without a …

Tweezepy: A Python package for calibrating forces in single-molecule video-tracking experiments

IL Morgan, OA Saleh - Plos one, 2021 - journals.plos.org
Single-molecule force spectroscopy (SMFS) instruments (eg, magnetic and optical tweezers)
often use video tracking to measure the three-dimensional position of micron-scale beads …

Deep learning-based size prediction for optical trapped nanoparticles and extracellular vesicles from limited bandwidth camera detection

D Boateng, K Chu, ZJ Smith, J Du… - Biomedical Optics Express, 2023 - opg.optica.org
Due to its ability to record position, intensity, and intensity distribution information, camera-
based monitoring of nanoparticles in optical traps can enable multi-parametric morpho …

Optimal calibration of optical tweezers with arbitrary integration time and sampling frequencies: a general framework

L Pérez-García, M Selin, A Ciarlo… - Biomedical Optics …, 2023 - opg.optica.org
Optical tweezers (OT) have become an essential technique in several fields of physics,
chemistry, and biology as precise micromanipulation tools and microscopic force …

School-aged outcomes following prenatal methamphetamine exposure: 7.5-year follow-up from the infant development, environment, and lifestyle study

N Eze, LM Smith, LL LaGasse, C Derauf… - The Journal of …, 2016 - Elsevier
Objective To assess the relationship between prenatal methamphetamine exposure (PME)
and behavior problems at age 7.5 years and the extent to which early adversity mediated …