Skeletal muscle energy metabolism during exercise

M Hargreaves, LL Spriet - Nature metabolism, 2020 - nature.com
The continual supply of ATP to the fundamental cellular processes that underpin skeletal
muscle contraction during exercise is essential for sports performance in events lasting …

Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

[HTML][HTML] Exercise, GLUT4, and skeletal muscle glucose uptake

EA Richter, M Hargreaves - Physiological reviews, 2013 - journals.physiology.org
Glucose is an important fuel for contracting muscle, and normal glucose metabolism is vital
for health. Glucose enters the muscle cell via facilitated diffusion through the GLUT4 glucose …

AMPK in health and disease

GR Steinberg, BE Kemp - Physiological reviews, 2009 - journals.physiology.org
The function and survival of all organisms is dependent on the dynamic control of energy
metabolism, when energy demand is matched to energy supply. The AMP-activated protein …

[HTML][HTML] AMPK in skeletal muscle function and metabolism

R Kjøbsted, JR Hingst, J Fentz, M Foretz… - The FASEB …, 2018 - ncbi.nlm.nih.gov
Skeletal muscle possesses a remarkable ability to adapt to various physiologic conditions.
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …

[PDF][PDF] Physical activity/exercise and type 2 diabetes

RJ Sigal, GP Kenny, DH Wasserman… - Diabetes …, 2004 - paulogentil.com
For decades, exercise has been consid-ered a cornerstone of diabetes management, along
with diet and medication. However, high-quality evidence on the importance of exercise and …

Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status

DG Hardie - Endocrinology, 2003 - academic.oup.com
All cells must maintain a high ratio of cellular ATP: ADP to survive. Because of the adenylate
kinase reaction (2ADP↔ ATP+ AMP), AMP rises whenever the ATP: ADP ratio falls, and a …

The molecular bases of training adaptation

VG Coffey, JA Hawley - Sports medicine, 2007 - Springer
Skeletal muscle is a malleable tissue capable of altering the type and amount of protein in
response to disruptions to cellular homeostasis. The process of exerciseinduced adaptation …

The regulation of fat metabolism during aerobic exercise

A Muscella, E Stefàno, P Lunetti, L Capobianco… - Biomolecules, 2020 - mdpi.com
Since the lipid profile is altered by physical activity, the study of lipid metabolism is a
remarkable element in understanding if and how physical activity affects the health of both …

Resistance exercise increases AMPK activity and reduces 4E‐BP1 phosphorylation and protein synthesis in human skeletal muscle

HC Dreyer, S Fujita, JG Cadenas… - The Journal of …, 2006 - Wiley Online Library
Resistance exercise is a potent stimulator of muscle protein synthesis and muscle cell
growth, with the increase in protein synthesis being detected within 2–3 h post‐exercise and …