The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review
MD Klok, S Jakobsdottir, ML Drent - Obesity reviews, 2007 - Wiley Online Library
Leptin and ghrelin are two hormones that have been recognized to have a major influence
on energy balance. Leptin is a mediator of long‐term regulation of energy balance …
on energy balance. Leptin is a mediator of long‐term regulation of energy balance …
Ghrelin: structure and function
M Kojima, K Kangawa - Physiological reviews, 2005 - journals.physiology.org
Small synthetic molecules called growth hormone secretagogues (GHSs) stimulate the
release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein …
release of growth hormone (GH) from the pituitary. They act through the GHS-R, a G protein …
Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
Ghrelin is a peptide predominantly produced by the stomach. Ghrelin displays strong GH-
releasing activity. This activity is mediated by the activation of the so-called GH …
releasing activity. This activity is mediated by the activation of the so-called GH …
Gender differences in insulin resistance, body composition, and energy balance
EB Geer, W Shen - Gender medicine, 2009 - Elsevier
Background: Men and women differ substantially in regard to degrees of insulin resistance,
body composition, and energy balance. Adipose tissue distribution, in particular the …
body composition, and energy balance. Adipose tissue distribution, in particular the …
A consensus on criteria for cure of acromegaly
Objective: The Acromegaly Consensus Group met in April 2009 to revisit the guidelines on
criteria for cure as defined in 2000. Participants: Participants included 74 neurosurgeons …
criteria for cure as defined in 2000. Participants: Participants included 74 neurosurgeons …
Ghrelin—a hormone with multiple functions
Ghrelin is brain-gut peptide with growth hormone-releasing and appetite-inducing activities.
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …
It is mainly secreted from the stomach mucosa but it is also expressed widely in different …
Opportunities in somatostatin research: biological, chemical and therapeutic aspects
G Weckbecker, I Lewis, R Albert, HA Schmid… - Nature reviews Drug …, 2003 - nature.com
Somatostatins—also known as somatotropin-release inhibiting factors (SRIFs)—are a family
of cyclopeptides that have broad inhibitory effects on the secretion of hormones such as …
of cyclopeptides that have broad inhibitory effects on the secretion of hormones such as …
[HTML][HTML] Obesity and androgens: facts and perspectives
R Pasquali - Fertility and sterility, 2006 - Elsevier
OBJECTIVE: This review discusses androgen status in male and female obesity, according
to their specific phenotype, and the main mechanisms responsible. DESIGN: Published data …
to their specific phenotype, and the main mechanisms responsible. DESIGN: Published data …
The migrating motor complex: control mechanisms and its role in health and disease
E Deloose, P Janssen, I Depoortere… - … reviews Gastroenterology & …, 2012 - nature.com
The migrating motor complex (MMC) is a cyclic, recurring motility pattern that occurs in the
stomach and small bowel during fasting; it is interrupted by feeding. The MMC is present in …
stomach and small bowel during fasting; it is interrupted by feeding. The MMC is present in …
Sleep enhances nocturnal plasma ghrelin levels in healthy subjects
A Dzaja, MA Dalal, H Himmerich… - American Journal …, 2004 - journals.physiology.org
Ghrelin, an endogenous ligand of the growth hormone secretagogue receptor, has been
shown to promote slow-wave sleep (SWS, non-REM sleep stages 3 and 4). Plasma levels of …
shown to promote slow-wave sleep (SWS, non-REM sleep stages 3 and 4). Plasma levels of …