Overcoming the Achilles' heel of photodynamic therapy
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …
Singlet oxygen: there is indeed something new under the sun
PR Ogilby - Chemical Society Reviews, 2010 - pubs.rsc.org
Singlet oxygen, O2 (a1Δg), the lowest excited electronic state of molecular oxygen, has
been known to the scientific community for∼ 80 years. It has a characteristic chemistry that …
been known to the scientific community for∼ 80 years. It has a characteristic chemistry that …
Singlet oxygen photophysics: from liquid solvents to mammalian cells
Molecular oxygen, O2, has long provided a cornerstone for studies in chemistry, physics,
and biology. Although the triplet ground state, O2 (X3Σg–), has garnered much attention, the …
and biology. Although the triplet ground state, O2 (X3Σg–), has garnered much attention, the …
Nanoparticles as vehicles for delivery of photodynamic therapy agents
D Bechet, P Couleaud, C Frochot, ML Viriot… - Trends in …, 2008 - cell.com
Photodynamic therapy (PDT) in cancer treatment involves the uptake of a photosensitizer by
cancer tissue followed by photoirradiation. The use of nanoparticles as carriers of …
cancer tissue followed by photoirradiation. The use of nanoparticles as carriers of …
Nonlinear optical properties of porphyrins
MO Senge, M Fazekas, EGA Notaras… - Advanced …, 2007 - Wiley Online Library
Porphyrins and phthalocyanines have outstanding chemical and thermal stability. The
macrocyclic structure and chemical reactivity of tetrapyrroles offers architectural flexibility …
macrocyclic structure and chemical reactivity of tetrapyrroles offers architectural flexibility …
Organically modified silica nanoparticles co-encapsulating photosensitizing drug and aggregation-enhanced two-photon absorbing fluorescent dye aggregates for …
We report energy-transferring organically modified silica nanoparticles for two-photon
photodynamic therapy. These nanoparticles co-encapsulate two-photon fluorescent dye …
photodynamic therapy. These nanoparticles co-encapsulate two-photon fluorescent dye …
Polymerization-enhanced two-photon photosensitization for precise photodynamic therapy
Two-photon excited photodynamic therapy (2PE-PDT) has attracted great attention in recent
years due to its great potential for deep-tissue and highly spatiotemporally precise cancer …
years due to its great potential for deep-tissue and highly spatiotemporally precise cancer …
Lifetime and diffusion of singlet oxygen in a cell
E Skovsen, JW Snyder, JDC Lambert… - The Journal of Physical …, 2005 - ACS Publications
In time-and spatially resolved experiments, singlet molecular oxygen, O2 (aΔg), was created
in a single nerve cell upon irradiation of a sensitizer incorporated in the cell nucleus using a …
in a single nerve cell upon irradiation of a sensitizer incorporated in the cell nucleus using a …
Nanophotosensitizers toward advanced photodynamic therapy of Cancer
Photodynamic therapy (PDT) is a non-invasive treatment modality for selective destruction of
cancer and other diseases and involves the colocalization of light, oxygen, and a …
cancer and other diseases and involves the colocalization of light, oxygen, and a …
Charge effect on the photoinactivation of Gram-negative and Gram-positive bacteria by cationic meso-substituted porphyrins
Background In recent times photodynamic antimicrobial therapy has been used to efficiently
destroy Gram (+) and Gram (-) bacteria using cationic porphyrins as photosensitizers. There …
destroy Gram (+) and Gram (-) bacteria using cationic porphyrins as photosensitizers. There …