Alternative pre-mRNA splicing increases the complexity of the proteome that can be
generated from the available genomic coding sequences. Dysregulation of the splicing …

Target of Rapamycin (TOR) is an evolutionarily conserved protein kinase that plays a central
role in coordinating cell growth with light availability, the diurnal cycle, energy availability …

For plants, light is the source of energy and the most relevant regulator of growth and
adaptations to the environment by inducing changes in gene expression at various levels …

Prostate cancer (PrCa) is highly heritable, and although rare variants contribute significantly
to PrCa risk, few have been identified to date. Herein, whole‐genome sequencing was …

Abstract Ca2+-insensitive and-sensitive E1 subunits of the 2-o xo g lutarate deh ydrogenase
c omplex (OGDHC) regulate tissue-specific NADH and ATP supply by mutually exclusive …

The mammalian target of rapamycin (mTOR) pathway is crucial in energy metabolism and
cell proliferation. Previously, we reported transcriptome-wide 3′-untranslated region (UTR) …

Background To investigate the expression and significance of mechanistic target of
rapamycin complex 1 (mTORC1) in diabetic retinopathy (DR), and to find new targets and …

(1) Background: A simplistic understanding of the central dogma falls short in correlating the
number of genes in the genome to the number of proteins in the proteome. Post …

Post-transcriptional regulations of mRNA transcripts such as alternative splicing and
alternative polyadenylation can affect the expression of genes without changing the …

Uterine fibroids (UFs), benign tumours prevalent in up to 80% of women of reproductive age,
are associated with significant morbidity, including abnormal uterine bleeding, pain and …