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Thiazole-based thiosemicarbazones: Synthesis, cytotoxicity evaluation and molecular docking study
SM Gomha, HA Abdelhady, DZH Hassain… - Drug Design …, 2021 - Taylor & Francis
Introduction Hybrid drug design has developed as a prime method for the development of
novel anticancer therapies that can theoretically solve much of the pharmacokinetic …
novel anticancer therapies that can theoretically solve much of the pharmacokinetic …
[HTML][HTML] Synthesis of novel aminothiazole derivatives as promising antiviral, antioxidant and antibacterial candidates
R Minickaitė, B Grybaitė, R Vaickelionienė… - International Journal of …, 2022 - mdpi.com
It is well-known that thiazole derivatives are usually found in lead structures, which
demonstrate a wide range of pharmacological effects. The aim of this research was to …
demonstrate a wide range of pharmacological effects. The aim of this research was to …
Microwave-Assisted One-Pot Telescoped Synthesis of 2-Amino-1,3-thiazoles, Selenazoles, Imidazo[1,2-a]pyridines, and Other Heterocycles from Alcohols
P Macías-Benítez, A Sierra-Padilla… - The Journal of …, 2024 - ACS Publications
Primary and secondary alcohols have been converted into 2-amino-1, 3-thiazoles under
microwave irradiation, employing trichloroisocyanuric acid (TCCA) as a dual oxidant and …
microwave irradiation, employing trichloroisocyanuric acid (TCCA) as a dual oxidant and …
Three-component p-TSA catalyzed synthesis of hydrazinyl thiazole derivatives
A direct single-pot three-component procedure for synthesizing bio-active hydrazinyl
thiazole derivatives has been demonstrated. The reaction involves substituted 2 …
thiazole derivatives has been demonstrated. The reaction involves substituted 2 …
Thiocyanatoarylation of Methyl Vinyl Ketone under Meerwein Conditions for the Synthesis of 2-Aminothiazole-Based Heterocyclic Systems
4-Aryl-3-thiocyanatobutan-2-ones were prepared by Meerwein reactions from methyl vinyl
ketone and aryldiazonium salts under copper (II) catalysis in 35–75% yields. α-Thiocyanato …
ketone and aryldiazonium salts under copper (II) catalysis in 35–75% yields. α-Thiocyanato …
Inhibiting brushite crystal growth: molecular docking exploration of Enhydra fluctuans phytoconstituents and their interaction with human serum albumin
In our preliminary in vitro studies, the Enhydra fluctuans extract demonstrated inhibition of
calcium phosphate (brushite) crystals. Human serum albumin (HSA) is known to act as a …
calcium phosphate (brushite) crystals. Human serum albumin (HSA) is known to act as a …
[HTML][HTML] One-pot synthesis of 4-aryl-2-aminothiazoles from styrenes and thioureas promoted by tribromoisocyanuric acid
VSC de Andrade, MCS de Mattos - Tetrahedron Letters, 2020 - Elsevier
A simple and efficient one-pot protocol has been developed for the conversion of styrenes
into 4-aryl-2-aminothiazoles using readily available starting materials. Tribromoisocyanuric …
into 4-aryl-2-aminothiazoles using readily available starting materials. Tribromoisocyanuric …
Synthesis, Reaction, and Biological Activity of Thiazoles
The current review aimed to provide an understanding of the preparation, reactions, and
biological action of thiazoles. The purpose of this review was to focus on the progress made …
biological action of thiazoles. The purpose of this review was to focus on the progress made …
Design, synthesis, cytotoxic activity and molecular docking studies of naphthyl pyrazolyl thiazole derivatives as anticancer agents
Novel series of heterocycliccompounds pairing hybrids pyrazole, naphthalene and
pyrazoline/thiazoldinemoieties were synthesized. The starting compounds pyrazolyl …
pyrazoline/thiazoldinemoieties were synthesized. The starting compounds pyrazolyl …
One-pot syntheses of substituted 2-aminothiazoles and 2-aminoselenazoles via Meerwein arylation of alkyl vinyl ketones
Both one-pot and two-step procedures for the synthesis of substituted 2-aminothiazoles and
2-aminoselenazoles are described. Anilines are first converted into arenediazonium …
2-aminoselenazoles are described. Anilines are first converted into arenediazonium …