Extracellular acidity and increased exosome release as key phenotypes of malignant tumors
M Logozzi, E Spugnini, D Mizzoni, R Di Raimo… - Cancer and Metastasis …, 2019 - Springer
The tumor milieu is characteristically acidic as a consequence of the fermentative
metabolism of glucose that results in massive accumulation of lactic acid within the …
metabolism of glucose that results in massive accumulation of lactic acid within the …
The emerging role of PIWI-interacting RNAs (piRNAs) in gastrointestinal cancers: An updated perspective
Simple Summary Gastrointestinal (GI) cancers are high mortality malignancies due to late
diagnosis, the presence of metastasis and drug resistance development. Novel and more …
diagnosis, the presence of metastasis and drug resistance development. Novel and more …
Exosomal PD-L1 and N-cadherin predict pulmonary metastasis progression for osteosarcoma patients
J Wang, H Zhang, X Sun, X Wang, T Ren… - Journal of …, 2020 - Springer
Background Recent studies indicated that exosomal programmed death-ligand 1 (PD-L1)
derived from cancers could induce immunosuppression and tumor pathogenesis. However …
derived from cancers could induce immunosuppression and tumor pathogenesis. However …
Exosomal miR-214 from endometrial stromal cells inhibits endometriosis fibrosis
D Wu, P Lu, X Mi, J Miao - MHR: Basic science of reproductive …, 2018 - academic.oup.com
STUDY QUESTION Is it possible to improve fibrosis in endometriosis by microRNA-214
delivery in exosomes? SUMMARY ANSWER Upregulation of miR-214 may inhibit …
delivery in exosomes? SUMMARY ANSWER Upregulation of miR-214 may inhibit …
The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer
Gallbladder cancer (GBC) is a highly fatal disease with poor prognosis and few therapeutic
alternatives. Molecular profiling has revealed that the deregulation in the ERK/MAPK …
alternatives. Molecular profiling has revealed that the deregulation in the ERK/MAPK …
[HTML][HTML] Primary Sclerosing Cholangitis-Associated Cholangiocarcinoma: From Pathogenesis to Diagnostic and Surveillance Strategies
E Catanzaro, E Gringeri, P Burra, M Gambato - Cancers, 2023 - mdpi.com
Cholangiocarcinoma (CCA) is the most common malignancy in patients with primary
sclerosing cholangitis (PSC), accounting for 2–8% of cases and being the leading cause of …
sclerosing cholangitis (PSC), accounting for 2–8% of cases and being the leading cause of …
Bile-derived circulating extracellular miR-30d-5p and miR-92a-3p as potential biomarkers for cholangiocarcinoma
Background Cholangiocarcinoma (CCA) is from cholangiocytes, and therefore bile is a
potentially rich source of biomarkers for CCA. The aim of the study was to identify and …
potentially rich source of biomarkers for CCA. The aim of the study was to identify and …
Droplet digital PCR quantification of miR-1290 as a circulating biomarker for pancreatic cancer
F Tavano, D Gioffreda, MR Valvano, O Palmieri… - Scientific reports, 2018 - nature.com
Droplet digital PCR was used to validate miR-1290 as circulating biomarker for pancreatic
cancer (PC). The diagnostic performance of miR-1290 was evaluate in 167 PC patients and …
cancer (PC). The diagnostic performance of miR-1290 was evaluate in 167 PC patients and …
Profiling of downregulated blood-circulating miR-150-5p as a novel tumor marker for cholangiocarcinoma
X Wu, M **a, D Chen, F Wu, Z Lv, Q Zhan, Y Jiao… - Tumor Biology, 2016 - Springer
Altered microRNA (miRNA) expression plays a role in cholangiocarcinoma (CCA)
development; thus, detection of blood-circulating miRNAs could be useful as CCA markers …
development; thus, detection of blood-circulating miRNAs could be useful as CCA markers …
[HTML][HTML] Exosomes in blood and cancer
ER Sauter - Translational Cancer Research, 2017 - tcr.amegroups.org
Exosomes are the smallest of the extracellular vesicles (EVs). They have been detected in a
variety of body fluids, including serum and plasma. Exosomes from tumor cells that are …
variety of body fluids, including serum and plasma. Exosomes from tumor cells that are …