[HTML][HTML] Extracellular vesicles in mental disorders: a state-of-art review

L Kong, D Zhang, S Huang, J Lai, L Lu… - … journal of biological …, 2023 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are nanoscale particles with various physiological functions
including mediating cellular communication in the central nervous system (CNS), which …

Dectin-1 signaling on colonic γδ T cells promotes psychosocial stress responses

X Zhu, S Sakamoto, C Ishii, MD Smith, K Ito… - Nature …, 2023 - nature.com
The intestinal immune system interacts with commensal microbiota to maintain gut
homeostasis. Furthermore, stress alters the microbiome composition, leading to impaired …

A new perspective on depression and neuroinflammation: Non-coding RNA

S Zhou, R Chen, Y She, X Liu, H Zhao, C Li… - Journal of psychiatric …, 2022 - Elsevier
The high incidence and relapse rate of depression, as well comorbidity with other diseases,
has made depression one of the primary causes of years of life lived with disability …

Stress induces major depressive disorder by a neutral sphingomyelinase 2-mediated accumulation of ceramide-enriched exosomes in the blood plasma

F Schumacher, A Carpinteiro, MJ Edwards… - Journal of Molecular …, 2022 - Springer
Major depressive disorder (MDD) is a very common, severe disease with a lifetime
prevalence of~ 10%. The pathogenesis of MDD is unknown and, unfortunately, therapy is …

Extracellular vesicles and the stress system

EA Makrygianni, GP Chrousos - Neuroendocrinology, 2023 - karger.com
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles that contain various
biomolecules, including nucleic acids, proteins and lipids, and are manufactured and …

Dendrimer-2PMPA delays muscle function loss and denervation in a murine model of amyotrophic lateral sclerosis

C Tallon, A Sharma, Z Zhang, AG Thomas, J Ng… - …, 2022 - Springer
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease where
muscle weakness and neuromuscular junction (NMJ) denervation precede motor neuron …

Tiny in size, big in impact: Extracellular vesicles as modulators of mood, anxiety and neurodevelopmental disorders

E Duarte-Silva, AC Oria, IP Mendonça… - Neuroscience & …, 2022 - Elsevier
Abstract Extracellular Vesicles (EVs) are tiny vesicles used by cells as means of cellular
communication, through which the function and state of a given cell can be changed. A body …

[HTML][HTML] Glutamine antagonist JHU083 improves psychosocial behavior and sleep deficits in EcoHIV-infected mice

BJ Bell, KR Hollinger, P Deme, S Sakamoto… - Brain, Behavior, & …, 2022 - Elsevier
Combined antiretroviral therapy ushered an era of survivable HIV infection in which people
living with HIV (PLH) conduct normal life activities and enjoy measurably extended …

The Emerging Role of Human Gut Bacteria Extracellular Vesicles in Mental Disorders and Develo** New Pharmaceuticals

E Louka, VL Koumandou - Current Issues in Molecular Biology, 2024 - mdpi.com
In recent years, further evidence has emerged regarding the involvement of extracellular
vesicles in various human physiopathological conditions such as Alzheimer's disease …

Exosomes may be the carrier of acupuncture treatment for major depressive disorder

Q Lyu, X Zhou, LQ Shi, HY Chen, M Lu… - Frontiers in Behavioral …, 2023 - frontiersin.org
The incidence of major depressive disorder (MDD) is increasing all over the world. There is
a great need for complementary or alternative therapies with high safety, few side effects …