Biomedical metal–organic framework materials: perspectives and challenges

A Wang, M Walden, R Ettlinger… - Advanced functional …, 2024 - Wiley Online Library
Metal–organic framework (MOF) materials are gaining significant interest in biomedical
research, owing to their high porosity, crystallinity, and structural and compositional diversity …

Reticular nanoscience: bottom-up assembly nanotechnology

J Andreo, R Ettlinger, O Zaremba, Q Pena… - Journal of the …, 2022 - ACS Publications
The chemistry of metal–organic and covalent organic frameworks (MOFs and COFs) is
perhaps the most diverse and inclusive among the chemical sciences, and yet it can be …

Cell‐based delivery systems: emerging carriers for immunotherapy

Z Li, Y Wang, Y Ding, L Repp… - Advanced Functional …, 2021 - Wiley Online Library
Immunotherapy is leading a paradigm shift in the treatment of various diseases, including
tumors, auto‐immune diseases, and infectious diseases. However, the limited response rate …

Cell‐in‐Catalytic‐Shell Nanoarchitectonics: Catalytic Empowerment of Individual Living Cells by Single‐Cell Nanoencapsulation

H Lee, J Park, N Kim, W Youn, G Yun… - Advanced …, 2022 - Wiley Online Library
Cell‐in‐shell biohybrid structures, synthesized by encapsulating individual living cells with
exogenous materials, have emerged as exciting functional entities for engineered living …

Improving normothermic machine perfusion and blood transfusion through biocompatible blood silicification

C Lei, Z Li, S Ma, Q Zhang, J Guo, Q Ouyang… - Proceedings of the …, 2024 - pnas.org
The growing world population and increasing life expectancy are driving the need to
improve the quality of blood transfusion, organ transplantation, and preservation. Here, to …

Challenges in cell membrane-camouflaged drug delivery systems: development strategies and future prospects

X Liu, X Zhong, C Li - Chinese Chemical Letters, 2021 - Elsevier
Extensive research has been performed on cell membrane camouflaged-based drug
delivery systems in recent years. Herein, we provide an overview of the challenges in …

Reticular Chemistry for Enhancing Bioentity Stability and Functional Performance

M Feng, C **ng, Y **, X Feng, Y Zhang… - Journal of the American …, 2024 - ACS Publications
Addressing the fragility of bioentities that results in instability and compromised performance
during storage and applications, reticular chemistry, specifically through metal–organic …

Bridging the In Vitro to In Vivo gap: Using the Chick Embryo Model to Accelerate Nanoparticle Validation and Qualification for In Vivo studies

KS Butler, CJ Brinker, HS Leong - ACS nano, 2022 - ACS Publications
We postulate that nanoparticles (NPs) for use in therapeutic applications have largely not
realized their clinical potential due to an overall inability to use in vitro results to predict NP …

Artificial bioaugmentation of biomacromolecules and living organisms for biomedical applications

J Cao, OT Zaremba, Q Lei, E Ploetz, S Wuttke, W Zhu - ACS nano, 2021 - ACS Publications
The synergistic union of nanomaterials with biomaterials has revolutionized synthetic
chemistry, enabling the creation of nanomaterial-based biohybrids with distinct properties for …

Immunoadjuvant-functionalized metal-organic frameworks: synthesis and applications in tumor immune modulation

C Zhao, W Song, J Wang, X Tang… - Chemical Communications, 2025 - pubs.rsc.org
Cancer immunotherapy, which leverages the body's immune system to recognize and attack
cancer cells, has made significant progress, particularly in the treatment of metastatic …