Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …

Conventional administration of drugs is limited by poor water solubility, low permeability,
and mediocre targeting. Safe and effective delivery of drugs and therapeutic agents remains …

Introduction: Silica materials, in particular mesoporous silicas, have demonstrated excellent
properties to enhance the oral bioavailability of poorly water-soluble drugs. Current research …

Porous materials are ubiquitous and exhibit properties suitable for depositing therapeutic
compounds. Drug loading in porous materials can protect the drug, control its release rate …

Abstract Hypothesis Solid lipid nanoparticles (SLNs) produced by conventional
microemulsion techniques using thermal heat have specific limitations (eg high …

The treatment and management of tuberculosis using conventional drug delivery systems
remain challenging due to the setbacks involved. The lengthy and costly treatment regime …

The objective of this research was to formulate ciprofloxacin (CIP) in solid lipid nanoparticles
(SLNs) in an attempt to develop a controlled drug delivery system. An ultrasonic melt …

The thermodynamically unstable nature of amorphous drugs has led to a persistent stability
issue of amorphous solid dispersions (ASDs). Lately, microwave-induced in situ …

In situ amorphization is a concept that allows to amorphize a given drug in its final dosage
form right before administration. Hence, this approach can potentially be used to circumvent …

A selection of porous silicas were combined with a model drug using a recently developed,
controlled microwave heating process to determine if the application of microwave …