Recent decades have seen a rise in the use of physics methods to study different societal
phenomena. This development has been due to physicists venturing outside of their …

Determining the transmissibility, prevalence and patterns of movement of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is central to our understanding …

In response to the emergence of SARS-CoV-2 variants of concern, the global scientific
community, through unprecedented effort, has sequenced and shared over 11 million …

The United Kingdom's COVID-19 epidemic during early 2020 was one of world's largest and
was unusually well represented by virus genomic sampling. We determined the fine-scale …

Background The burden and influence of health-care associated severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the …

Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of
microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly …

Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK …

How viruses evolve within hosts can dictate infection outcomes; however, reconstructing this
process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to …

Summary Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2 infection and
was first reported in central China in December 2019. Extensive molecular surveillance in …

Abstract The recent Ebola and Zika epidemics demonstrate the need for the continuous
surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases. Fast …