Amyloid refers to insoluble protein aggregates that are responsible for amyloid diseases but
are also implicated in important physiological functions (functional amyloids). The …

Alpha‐synuclein (ASYN) is a major constituent of the typical protein aggregates observed in
several neurodegenerative diseases that are collectively referred to as synucleinopathies. A …

The misfolding and aggregation of amyloid-β (Aβ) peptides into amyloid fibrils is regarded
as one of the causative events in the pathogenesis of Alzheimer's disease (AD) …

Several plant-derived natural compounds are known to exhibit anti-amyloid aggregation
activity which makes them attractive as potential therapies to treat Alzheimer's disease. The …

Protein aggregation underlies an array of human diseases, yet only one small-molecule
therapeutic targeting this process has been successfully developed to date. Here, we …

Exciting new technological developments have pushed the boundaries of structural biology,
and have enabled studies of biological macromolecules and assemblies that would have …

Protein aggregation into highly ordered, regularly repeated cross-β sheet structures called
amyloid fibrils is closely associated to human disorders such as neurodegenerative …

Protein misfolding and abnormal assembly could lead to aggregates such as oligomer, proto‐
fibril, mature fibril, and senior amyloid plaques, which are associated with the pathogenesis …

Protein misfolding and abnormal self-assembly lead to the aggregates of oligomers, fibrils,
or senior amyloid β (Aβ) plaques, which are associated with the pathogenesis of many …

The abnormal fibrillogenesis of amyloid peptides such as amyloid fibril and senior amyloid
plaques, is associated with the pathogenesis of many amyloid diseases. Hence, modulation …