High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

A nanoelectrode array for obtaining intracellular recordings from thousands of connected neurons

J Abbott, T Ye, K Krenek, RS Gertner, S Ban… - Nature biomedical …, 2020 - nature.com
Current electrophysiological or optical techniques cannot reliably perform simultaneous
intracellular recordings from more than a few tens of neurons. Here we report a …

Electrophysiology read-out tools for brain-on-Chip biotechnology

C Forro, D Caron, GN Angotzi, V Gallo, L Berdondini… - Micromachines, 2021 - mdpi.com
Brain-on-Chip (BoC) biotechnology is emerging as a promising tool for biomedical and
pharmaceutical research applied to the neurosciences. At the convergence between lab-on …

A multimodal CMOS MEA for high-throughput intracellular action potential measurements and impedance spectroscopy in drug-screening applications

CM Lopez, HS Chun, S Wang, L Berti… - IEEE Journal of Solid …, 2018 - ieeexplore.ieee.org
Multi-electrode arrays (MEAs) are a candidate technology to screen cardiotoxicity in vitro
because they enable noninvasive recording of cardiac beating rate, electrical field potential …

A CMOS pixelated nanocapacitor biosensor platform for high-frequency impedance spectroscopy and imaging

F Widdershoven, A Cossettini… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
We describe the realization of a fully electronic label-free temperature-controlled biosensing
platform aimed to overcome the Debye screening limit over a wide range of electrolyte salt …

An EMG interface comprising a flexible a-IGZO active electrode matrix and a 65-nm CMOS IC

E Genco, C Garripoli… - IEEE Journal of Solid …, 2023 - ieeexplore.ieee.org
In this work, a 4 active electrode (AE) matrix integrated on a flexible foil substrate to monitor
muscular contraction is presented. The electrodes and their front ends (FEs)(ie, AEs) are …

A review of CMOS electrochemical readout interface designs for biomedical assays

SY Lu, SS Shan, TH Lu, YH Yeh, SC Kuo… - IEEE Sensors …, 2021 - ieeexplore.ieee.org
Electrochemical sensing has been widely applied to a variety of applications involving
disease diagnosis due to its ability to measure targets directly, fast response, and high …

A multimodal and multifunctional CMOS cellular interfacing array for digital physiology and pathology featuring an ultra dense pixel array and reconfigurable sampling …

AY Wang, Y Sheng, W Li, D Jung… - … Circuits and Systems, 2022 - ieeexplore.ieee.org
The article presents a fully integrated multimodal and multifunctional CMOS
biosensing/actuating array chip and system for multi-dimensional cellular/tissue …

The EcoChip: A wireless multi-sensor platform for comprehensive environmental monitoring

M Sylvain, F Lehoux, S Morency… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
This paper presents the EcoChip, a new system based on the state-of-the-art electro-
chemical impedance (EIS) technologies allowing the growth of single strain organisms …

A 1024-Channel 10-Bit 36-W/ch CMOS ROIC for Multiplexed GFET-Only Sensor Arrays in Brain Map**

J Cisneros-Fernández… - … Circuits and Systems, 2021 - ieeexplore.ieee.org
This paper presents a 1024-channel neural read-out integrated circuit (ROIC) for solution-
gated GFET sensing probes in massive ECoG brain map**. The proposed time-domain …