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Cell–extracellular matrix mechanotransduction in 3D
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …
including differentiation, migration and proliferation, through mechanotransduction. Studies …
Single-molecule localization microscopy
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
techniques that dramatically improve spatial resolution over standard, diffraction-limited …
Directed cell migration towards softer environments
How cells sense tissue stiffness to guide cell migration is a fundamental question in
development, fibrosis and cancer. Although durotaxis—cell migration towards increasing …
development, fibrosis and cancer. Although durotaxis—cell migration towards increasing …
Regulation of macrophage polarization through surface topography design to facilitate implant-to-bone osteointegration
Proper immune responses are critical for successful biomaterial implantation. Here, four
scales of honeycomb-like TiO2 structures were custom made on titanium (Ti) substrates to …
scales of honeycomb-like TiO2 structures were custom made on titanium (Ti) substrates to …
Static and dynamic: evolving biomaterial mechanical properties to control cellular mechanotransduction
The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
biological, and chemical signals to embraced cells. Increasing evidence suggests that …
Super-resolution microscopy for structural cell biology
Super-resolution microscopy techniques, and specifically single-molecule localization
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …
The extracellular matrix in tumor progression and metastasis
JA Eble, S Niland - Clinical & experimental metastasis, 2019 - Springer
The extracellular matrix (ECM) constitutes the scaffold of tissues and organs. It is a complex
network of extracellular proteins, proteoglycans and glycoproteins, which form …
network of extracellular proteins, proteoglycans and glycoproteins, which form …
Visualizing and discovering cellular structures with super-resolution microscopy
Super-resolution microscopy has overcome a long-held resolution barrier—the diffraction
limit—in light microscopy and enabled visualization of previously invisible molecular details …
limit—in light microscopy and enabled visualization of previously invisible molecular details …
Cellulose biomaterials for tissue engineering
RJ Hickey, AE Pelling - Frontiers in bioengineering and …, 2019 - frontiersin.org
In this review, we highlight the importance of nanostructure of cellulose-based biomaterials
to allow cellular adhesion, the contribution of nanostructure to macroscale mechanical …
to allow cellular adhesion, the contribution of nanostructure to macroscale mechanical …
The cytoskeleton in phagocytosis and macropinocytosis
Cells of the innate immune system, notably macrophages, neutrophils and dendritic cells,
perform essential antimicrobial and homeostatic functions. These functions rely on the …
perform essential antimicrobial and homeostatic functions. These functions rely on the …