Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

Ion mobility spectrometry (IMS) coupled to mass spectrometry (MS) has seen spectacular
growth over the last two decades. Increasing IMS sensitivity and capacity with improvements …

A benchmark comparison between two ion mobility and collision cross-section (CCS)
calculators, MOBCAL and IMoS, is presented here as a standard to test the efficiency and …

A pending issue in linking ion mobility measurements to ion structures is that the collisional
cross section (CCS, the measured structural parameter in ion mobility spectrometry) of an …

Structural characterization of ions in the gas phase is facilitated by measurement of ion
collision cross sections (CCS) using techniques such as ion mobility spectrometry. Further …

Charge detection mass spectrometry is used to measure the mass, charge, MSn and
mobility of an individual ion produced by electrospray ionization of a 8 MDa polyethylene …

Protein analyses by electrospray ionization (ESI) mass spectrometry can suffer from
interferences caused by nonvolatile salts. The mechanistic basis of this effect remains to be …

Theoretical and experimental analyses of the steady state, bipolar diffusion charge
distribution on nanoparticles are reviewed. This charge distribution plays a critical role in …

We utilized a differential mobility analyzer–mass spectrometer (DMA–MS) with a high
resolving power (~ 45) parallel plate DMA to measure the masses and mobilities of positive …

Described herein is the development of a 3D-printed drift-tube ion mobility spectrometer
(IMS) which operates in the open air and is capable of being coupled to any mass …