Epstein–Barr virus: how its lytic phase contributes to oncogenesis

Q Rosemarie, B Sugden - Microorganisms, 2020 - mdpi.com
Epstein–Barr Virus (EBV) contributes to the development of lymphoid and epithelial
malignancies. While EBV's latent phase is more commonly associated with EBV-associated …

Herpesviruses and their host cells: a successful liaison

B Adler, C Sattler, H Adler - Trends in microbiology, 2017 - cell.com
During a long history of coevolution, herpesviruses have reached a fine-tuned balance with
their hosts, allowing them to successfully persist and spread to new hosts without causing …

[HTML][HTML] Genome-wide profiling of Epstein-Barr virus integration by targeted sequencing in Epstein-Barr virus associated malignancies

M Xu, WL Zhang, Q Zhu, S Zhang, Y Yao, T **ang… - Theranostics, 2019 - ncbi.nlm.nih.gov
Abstract Rationale: Epstein-Barr virus (EBV) is associated with multiple malignancies with
expression of viral oncogenic proteins and chronic inflammation as major mechanisms …

Conserved herpesvirus protein kinases target SAMHD1 to facilitate virus replication

K Zhang, DW Lv, R Li - Cell reports, 2019 - cell.com
To ensure a successful infection, herpesviruses have developed elegant strategies to
counterbalance the host anti-viral responses. Sterile alpha motif and HD domain 1 …

Proteomic and phosphoproteomic analysis of responses to enterovirus A71 infection reveals novel targets for antiviral and viral replication

D Lin, X Dong, X **ao, Z **ang, X Lei, J Wang - Antiviral Research, 2023 - Elsevier
Hand, foot, and mouth disease (HFMD) is a common infectious disease in infants and
children, especially those under five years of age. EV-A71 is a common pathogen that …

SUMOylation of the m6A reader YTHDF2 by PIAS1 promotes viral RNA decay to restrict EBV replication

FG Sugiokto, F Saiada, K Zhang, R Li - Mbio, 2024 - Am Soc Microbiol
ABSTRACT YTH N6-methyladenosine RNA-binding protein F2 (YTHDF2) is a member of
the YTH protein family that binds to N6-methyladenosine (m6A)-modified RNA, regulating …

Interferon regulatory factor 8 regulates caspase-1 expression to facilitate Epstein-Barr virus reactivation in response to B cell receptor stimulation and chemical …

DW Lv, K Zhang, R Li - PLoS pathogens, 2018 - journals.plos.org
Interferon regulatory factor 8 (IRF8), also known as interferon consensus sequence-binding
protein (ICSBP), is a transcription factor of the IRF family. IRF8 plays a key role in normal B …

Take your PIKK: tumour viruses and DNA damage response pathways

NJ Pancholi, AM Price… - … Transactions of the …, 2017 - royalsocietypublishing.org
Viruses regulate cellular processes to facilitate viral replication. Manipulation of nuclear
proteins and pathways by nuclear replicating viruses often causes cellular genome …

Berberine in human oncogenic herpesvirus infections and their linked cancers

M Šudomová, K Berchová-Bímová, S Marzocco… - Viruses, 2021 - mdpi.com
Human herpesviruses are known to induce a broad spectrum of diseases, ranging from
common cold sores to cancer, and infections with some types of these viruses, known as …

Tyrosine phosphorylation as a widespread regulatory mechanism in prokaryotes

LJ Getz, CS Runte, JK Rainey… - Journal of Bacteriology, 2019 - Am Soc Microbiol
Phosphorylation events modify bacterial and archaeal proteomes, imparting cells with rapid
and reversible responses to specific environmental stimuli or niches. Phosphorylated …