[HTML][HTML] Thiazole ring—A biologically active scaffold

A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

An overview of the synthesis and antimicrobial, antiprotozoal, and antitumor activity of thiazole and bisthiazole derivatives

AM Borcea, I Ionuț, O Crișan, O Oniga - Molecules, 2021 - mdpi.com
Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …

Coordination chemistry of thiazoles, isothiazoles and thiadiazoles

LMT Frija, AJL Pombeiro, MN Kopylovich - Coordination Chemistry …, 2016 - Elsevier
Thiazole derived compounds have great potential in medicinal-and agro-chemistries,
catalysis, cosmetic industry, corrosion protection, light harvesting, production of light-emitting …

One-pot three-component synthesis of 1, 2, 3-triazoles using magnetic NiFe 2 O 4–glutamate–Cu as an efficient heterogeneous catalyst in water

J Lu, EQ Ma, YH Liu, YM Li, LP Mo, ZH Zhang - RSC Advances, 2015 - pubs.rsc.org
A novel magnetic NiFe2O4 supported glutamate–copper catalyst was prepared in a
convenient and ecofriendly manner and characterized using FTIR, XRD, EDX, TEM, SEM …

Substrate-controlled three-component synthesis of diverse fused heterocycles

AA Peshkov, D Gapanenok, A Puzyk… - The Journal of …, 2023 - ACS Publications
A chemoselective strategy toward a variety of fused heterocyclic scaffolds relying on a three-
component condensation of heterocyclic ketene aminals (HKAs) or corresponding …

Aldo‐X Bifunctional Building Blocks for the Synthesis of Heterocycles

P Ravichandiran, B Lai, Y Gu - The Chemical Record, 2017 - Wiley Online Library
Compounds containing oxygen, nitrogen, or sulfur atoms inside the rings are attracting much
attention and interest due to their biological importance. In recent years, several methods for …

Multicomponent synthesis of diphenyl-1, 3-thiazole-barbituric acid hybrids and their fluorescence property studies

A Mahata, P Bhaumick, AK Panday, R Yadav… - New Journal of …, 2020 - pubs.rsc.org
A series of novel diphenyl-1, 3-thiazole linked barbituric acid hybrids (4) were prepared by
two catalyst-free methods from readily available starting materials. The reaction of …

In-vitro and in-silico assessment of thiazole-thiazolidinone derivatives as selective inhibitors of urease and α-glucosidase

Y Khan, R Hussain, W Rehman, S Khan… - Future Medicinal …, 2024 - Taylor & Francis
Aims Current research work aims to synthesize hybrid compounds with a thiazole-
thiazolidinone structure, as potent inhibitors of urease and α-glucosidase enzymes …

FeCl 3 or MeSO 3 H-promoted multicomponent reactions for facile synthesis of structurally diverse furan analogues

X Chang, X Zhang, Z Chen - Organic & biomolecular chemistry, 2018 - pubs.rsc.org
An intriguing conversion of arylglyoxal, cyclic dicarbonyl compounds and phenols to diverse
furan analogues under FeCl3 or MeSO3H catalysis is reported. Utilizing this synthetic …

Aspirin: an efficient catalyst for synthesis of bis (pyrazol-5-ols), dihydropyrano[2,3-c]pyrazoles and spiropyranopyrazoles in an environmentally benign manner

M Fatahpour, F Noori Sadeh, N Hazeri… - Journal of the Iranian …, 2017 - Springer
This article aimed to present two facile and environmental friendly routes for the rapid
assembly of biologically active compounds including pyrazol core using aspirin as a novel …