Most chemotherapeutics elevate intracellular levels of reactive oxygen species (ROS), and
many can alter redox-homeostasis of cancer cells. It is widely accepted that the anticancer …

Human pluripotent stem cells (hPSCs)-derived cardiovascular progenitor cells (CVPCs) are
a promising source for myocardial repair, while the mechanisms remain largely unknown …

A huge variety of mathematical models have been used to investigate collective cell
migration. The aim of this brief review is twofold: to present a number of modelling …

Having the ability to work with complex models can be highly beneficial. However, complex
models often have intractable likelihoods, so methods that involve evaluation of the …

The prion hypothesis states that misfolded proteins can act as infectious agents that
template the misfolding and aggregation of healthy proteins to transmit a disease. Increasing …

The scratch assay is an in vitro technique used to assess the contribution of molecular and
cellular mechanisms to cell migration. The assay can also be used to evaluate therapeutic …

We examine the practical identifiability of parameters in a spatio-temporal reaction–diffusion
model of a scratch assay. Experimental data involve fluorescent cell cycle labels, providing …

The Fisher–Kolmogorov–Petrovsky–Piskunov model, also known as the Fisher–KPP model,
supports travelling wave solutions that are successfully used to model numerous invasive …

The coordination of cell proliferation and migration in growing tissues is crucial in
development and regeneration but remains poorly understood. Here, we find that, while …

Background Standard methods for quantifying IncuCyte ZOOM™ assays involve
measurements that quantify how rapidly the initially-vacant area becomes re-colonised with …