The corneal fibrosis response to epithelial–stromal injury

AAM Torricelli, A Santhanam, J Wu, V Singh… - Experimental eye …, 2016 - Elsevier
The corneal wound healing response, including the development of stromal opacity in some
eyes, is a process that often leads to scarring that occurs after injury, surgery or infection to …

Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy

MV Netto, RR Mohan, R Ambrósio Jr, AEK Hutcheon… - Cornea, 2005 - journals.lww.com
Purpose: The corneal wound healing response is of particular relevance for refractive
surgical procedures since it is a major determinant of efficacy and safety. The purpose of this …

Novel therapies for the prevention of fibrosis in glaucoma filtration surgery

CG Shao, NR Sinha, RR Mohan, AD Webel - Biomedicines, 2023 - mdpi.com
Conjunctival fibrosis remains the major impediment to the success of glaucoma filtration
surgery. Anti-metabolites remain the gold standard for mitigating post-surgical fibrosis, but …

Effect of prophylactic and therapeutic mitomycin C on corneal apoptosis, cellular proliferation, haze, and long-term keratocyte density in rabbits

MV Netto, RR Mohan, S Sinha… - Journal of Refractive …, 2006 - journals.healio.com
ABSTRACT PURPOSE: To determine the mechanism through which topical mitomycin C
prevents and treats corneal haze after photorefractive keratectomy (PRK) and to examine …

Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes

C Gambato, A Ghirlando, E Moretto, F Busato… - Ophthalmology, 2005 - Elsevier
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH)
after photorefractive keratectomy (PRK) in highly myopic eyes. DESIGN: Prospective, double …

Mitomycin C in corneal refractive surgery

MA Teus, L de Benito-Llopis, JL Alió - Survey of ophthalmology, 2009 - Elsevier
Mitomycin C has played a deciding role in the current revival of excimer laser surface
ablation techniques. We review the literature regarding mechanism of action of mitomycin C …

A critical overview of the biological effects of mitomycin C application on the cornea following refractive surgery

E Arranz-Marquez, A Katsanos, VP Kozobolis… - Advances in …, 2019 - Springer
During the last 2 decades, modifying the shape of the cornea by means of laser
photoablation has emerged as a successful and popular treatment option for refractive …

Biological effects of mitomycin C on late corneal haze stromal fibrosis following PRK

RC de Oliveira, SE Wilson - Experimental eye research, 2020 - Elsevier
This review details the current understanding of the mechanism of action and corneal effects
of mitomycin C (MMC) for prophylactic prevention of stromal fibrosis after photorefractive …

Mitomycin C: biological effects and use in refractive surgery

MR Santhiago, MV Netto, SE Wilson - Cornea, 2012 - journals.lww.com
Purpose: To provide an overview of the safety and efficacy of mitomycin C (MMC) as
adjuvant therapy after refractive surgery procedures. Methods: Literature review. Results …

[HTML][HTML] Mitomycin C-induced reduction of keratocytes and fibroblasts after photorefractive keratectomy

JH Pak, SY Lee, H Tchah - Investigative ophthalmology & visual …, 2004 - arvojournals.org
purpose. To investigate the effects of mitomycin C (MMC) on the number of keratocytes and
the proliferation of fibroblasts after photorefractive keratectomy (PRK) and exposure to …