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Cell–extracellular matrix mechanotransduction in 3D
A Saraswathibhatla, D Indana… - Nature Reviews Molecular …, 2023 - nature.com
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …
including differentiation, migration and proliferation, through mechanotransduction. Studies …
Chemical strategies to engineer hydrogels for cell culture
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …
Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity
H Cao, L Duan, Y Zhang, J Cao, K Zhang - Signal transduction and …, 2021 - nature.com
Hydrogel is a type of versatile platform with various biomedical applications after rational
structure and functional design that leverages on material engineering to modulate its …
structure and functional design that leverages on material engineering to modulate its …
Engineering the multiscale complexity of vascular networks
The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …
nutrients through vascular networks that pervade nearly all tissues in the body …
Dynamic and reconfigurable materials from reversible network interactions
MJ Webber, MW Tibbitt - Nature Reviews Materials, 2022 - nature.com
Polymer materials provide solutions to some of the most pressing environmental,
manufacturing and health-care challenges. Traditional thermoplastic and thermoset …
manufacturing and health-care challenges. Traditional thermoplastic and thermoset …
Stimuli-responsive dynamic hydrogels: design, properties and tissue engineering applications
S Amirthalingam, AK Rajendran, YG Moon… - Materials …, 2023 - pubs.rsc.org
The field of tissue engineering and regenerative medicine has been evolving at a rapid pace
with numerous novel and interesting biomaterials being reported. Hydrogels have come a …
with numerous novel and interesting biomaterials being reported. Hydrogels have come a …
Tunable hydrogel viscoelasticity modulates human neural maturation
Human-induced pluripotent stem cells (hiPSCs) have emerged as a promising in vitro model
system for studying neurodevelopment. However, current models remain limited in their …
system for studying neurodevelopment. However, current models remain limited in their …
Viscoelastic cell microenvironment: hydrogel‐based strategy for recapitulating dynamic ECM mechanics
Y Ma, T Han, Q Yang, J Wang, B Feng… - Advanced Functional …, 2021 - Wiley Online Library
The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …
displays time‐dependent responses to deformation or mechanical loading, in terms of …
Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
3D printing of microgel scaffolds with tunable void fraction to promote cell infiltration
AJ Seymour, S Shin… - Advanced healthcare …, 2021 - Wiley Online Library
Granular, microgel‐based materials have garnered interest as promising tissue engineering
scaffolds due to their inherent porosity, which can promote cell infiltration. Adapting these …
scaffolds due to their inherent porosity, which can promote cell infiltration. Adapting these …