Quantification of microglial activation through morphometric analysis has long been a staple
of the neuroimmunologist's toolkit. Microglial morphological phenomics can be conducted …

Microglial cells are the scions of foetal macrophages which invade the neural tube early
during embryogenesis. The nervous tissue environment instigates the phenotypic …

Neuroinflammation is a hallmark of many neurological diseases including traumatic brain
injury (TBI), which is usually characterized by two pathological hallmarks: activation of …

Microglia are the resident innate immune cells of the central nervous system (CNS)
parenchyma. To determine the impact of microglia on disease development and progression …

Microglia are specialized immune cells unique to the central nervous system (CNS).
Microglia have a highly plastic morphology that changes rapidly in response to injury or …

Axonal regeneration and functional recovery are poor after spinal cord injury (SCI), typified
by the formation of an injury scar. While this scar was traditionally believed to be primarily …

The activation of microglia and the infiltration of macrophages are hallmarks of
neuroinflammation after acute brain injuries, including traumatic brain injury (TBI). The two …

Background Ischemic stroke elicits a complex and sustained immune response in the brain.
Immunomodulatory treatments have long held promise for improving stroke outcomes, yet …

Stroke is a leading cause of death and disability worldwide, but there are a limited number of
therapies that improve patients' functional recovery. The complicated mechanisms of post …

Sleep is a natural physiological state, tightly regulated through several neuroanatomical and
neurochemical systems, which is essential to maintain physical and mental health. Recent …