Schistosome feeding and regurgitation

PJ Skelly, AA Da'dara, XH Li, W Castro-Borges… - PLoS …, 2014 - journals.plos.org
Schistosomes are parasitic flatworms that infect> 200 million people worldwide, causing the
chronic, debilitating disease schistosomiasis. Unusual among parasitic helminths, the long …

Schistosoma genomics: new perspectives on schistosome biology and host-parasite interaction

ZG Han, PJ Brindley, SY Wang… - Annual review of …, 2009 - annualreviews.org
Schistosomiasis, caused mainly by Schistosoma japonicum, S. mansoni, and S.
hematobium, remains one of the most prevalent and serious parasitic diseases worldwide …

An Atlas for Schistosoma mansoni Organs and Life-Cycle Stages Using Cell Type-Specific Markers and Confocal Microscopy

JJ Collins III, RS King, A Cogswell… - PLoS neglected …, 2011 - journals.plos.org
Schistosomiasis (bilharzia) is a tropical disease caused by trematode parasites
(Schistosoma) that affects hundreds of millions of people in the develo** world. Currently …

Advances in new target molecules against schistosomiasis: A comprehensive discussion of physiological structure and nutrient intake

P Zhu, K Wu, C Zhang, SS Batool, A Li, Z Yu… - PLoS …, 2023 - journals.plos.org
Schistosomiasis, a severe parasitic disease, is primarily caused by Schistosoma mansoni,
Schistosoma japonicum, or Schistosoma haematobium. Currently, praziquantel is the only …

RNA Interference in Schistosoma mansoni Schistosomula: Selectivity, Sensitivity and Operation for Larger-Scale Screening

S Štefanić, J Dvořák, M Horn, S Braschi… - PLoS neglected …, 2010 - journals.plos.org
Background The possible emergence of resistance to the only available drug for
schistosomiasis spurs drug discovery that has been recently incentivized by the availability …

Suppression of mRNAs Encoding Tegument Tetraspanins from Schistosoma mansoni Results in Impaired Tegument Turnover

MH Tran, TC Freitas, L Cooper, S Gaze… - PLoS …, 2010 - journals.plos.org
Schistosomes express a family of integral membrane proteins, called tetraspanins (TSPs), in
the outer surface membranes of the tegument. Two of these tetraspanins, Sm-TSP-1 and Sm …

Molecular characterization of a Trichinella spiralis aspartic protease and its facilitation role in larval invasion of host intestinal epithelial cells

J Xu, RD Liu, SJ Bai, HN Hao, WW Yue… - PLoS Neglected …, 2020 - journals.plos.org
Background T. spiralis aspartic protease has been identified in excretion/secretion (ES)
proteins, but its roles in larval invasion are unclear. The aim of this study was to characterize …

Elucidating the transcriptome of Fasciola hepatica—a key to fundamental and biotechnological discoveries for a neglected parasite

ND Young, RS Hall, AR Jex, C Cantacessi… - Biotechnology …, 2010 - Elsevier
Liver flukes of animals are parasitic flatworms (Platyhelminthes: Digenea) of major
socioeconomic importance in many countries. Key representatives, such as Fasciola …

[HTML][HTML] Current status and future prospects of protein vaccine candidates against Schistosoma mansoni infection

T Eyayu, AJ Zeleke, L Worku - Parasite Epidemiology and Control, 2020 - Elsevier
Schistosomiasis is an acute and chronic tropical parasitic disease caused by blood dwelling
worm of the genus Schistosoma. It is the most destructive disease globally and is a major …

Helminth genomics: The implications for human health

PJ Brindley, M Mitreva, E Ghedin… - PLoS neglected tropical …, 2009 - journals.plos.org
More than two billion people (one-third of humanity) are infected with parasitic roundworms
or flatworms, collectively known as helminth parasites. These infections cause diseases that …