Rehabilitation in amyotrophic lateral sclerosis: why it matters

S Majmudar, J Wu, S Paganoni - Muscle & nerve, 2014 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that results in a
constellation of problematic symptoms and a high patient and caregiver burden …

Assessment of dysarthria and dysphagia in patients with amyotrophic lateral sclerosis: Review of the current evidence

J Lee, A Madhavan, E Krajewski… - Muscle & …, 2021 - Wiley Online Library
Bulbar dysfunction is a common presentation of amyotrophic lateral sclerosis (ALS) and
significantly impacts quality of life of people with ALS (PALS). The current paper reviews …

Vowel acoustics in Parkinson's disease and multiple sclerosis: Comparison of clear, loud, and slow speaking conditions

K Tjaden, J Lam, G Wilding - 2013 - ASHA
Purpose The impact of clear speech, increased vocal intensity, and rate reduction on
acoustic characteristics of vowels was compared in speakers with Parkinson's disease (PD) …

“You say severe, I say mild”: Toward an empirical classification of dysarthria severity

KL Stipancic, KM Palmer, HP Rowe, Y Yunusova… - Journal of Speech …, 2021 - ASHA
Purpose: The main purpose of this study was to create an empirical classification system for
speech severity in patients with dysarthria secondary to amyotrophic lateral sclerosis (ALS) …

Speech movement measures as markers of bulbar disease in amyotrophic lateral sclerosis

S Shellikeri, JR Green, M Kulkarni, P Rong… - Journal of Speech …, 2016 - ASHA
Purpose The goal of this study was to identify the effects of amyotrophic lateral sclerosis
(ALS) on tongue and jaw control, both cross-sectionally and longitudinally. The data were …

Predicting speech intelligibility decline in amyotrophic lateral sclerosis based on the deterioration of individual speech subsystems

P Rong, Y Yunusova, J Wang, L Zinman, GL Pattee… - PloS one, 2016 - journals.plos.org
Purpose To determine the mechanisms of speech intelligibility impairment due to neurologic
impairments, intelligibility decline was modeled as a function of co-occurring changes in the …

Comprehensive rehabilitative care across the spectrum of amyotrophic lateral sclerosis

S Paganoni, C Karam, N Joyce, R Bedlack… - …, 2015 - content.iospress.com
BACKGROUND: Amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) is a
neurodegenerative disease that results in progressive muscle weakness and wasting. There …

Quantifying articulatory impairments in neurodegenerative motor diseases: A sco** review and meta-analysis of interpretable acoustic features

HP Rowe, S Shellikeri, Y Yunusova… - … Journal of Speech …, 2023 - Taylor & Francis
Abstract Purpose Neurodegenerative motor diseases (NMDs) have devastating effects on
the lives of patients and their loved ones, in part due to the impact of neurologic …

[HTML][HTML] Objectively monitoring amyotrophic lateral sclerosis patient symptoms during clinical trials with sensors: observational study

L Garcia-Gancedo, ML Kelly, A Lavrov… - JMIR mHealth and …, 2019 - mhealth.jmir.org
Background: Objective symptom monitoring of patients with Amyotrophic Lateral Sclerosis
(ALS) has the potential to provide an important source of information to evaluate the impact …

Automated acoustic analysis of oral diadochokinesis to assess bulbar motor involvement in amyotrophic lateral sclerosis

P Rong - Journal of Speech, Language, and Hearing Research, 2020 - ASHA
Purpose The purpose of this article was to validate a novel acoustic analysis of oral
diadochokinesis (DDK) in assessing bulbar motor involvement in amyotrophic lateral …