International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Epithelial barrier hypothesis: effect of the external exposome on the microbiome and epithelial barriers in allergic disease

Z Celebi Sozener, B Ozdel Ozturk, P Cerci, M Turk… - Allergy, 2022 - Wiley Online Library
Environmental exposure plays a major role in the development of allergic diseases. The
exposome can be classified into internal (eg, aging, hormones, and metabolic processes) …

Early life microbial exposures and allergy risks: opportunities for prevention

H Renz, C Skevaki - Nature Reviews Immunology, 2021 - nature.com
Allergies, including asthma, food allergy and atopic dermatitis, are increasing in prevalence,
particularly in westernized countries. Although a detailed mechanistic explanation for this …

Biodiversity and human health: mechanisms and evidence of the positive health effects of diversity in nature and green spaces

R Aerts, O Honnay… - British medical …, 2018 - academic.oup.com
Introduction Natural environments and green spaces provide ecosystem services that
enhance human health and well-being. They improve mental health, mitigate allergies and …

A biodiversity hypothesis

T Haahtela - Allergy, 2019 - Wiley Online Library
Biodiversity hypothesis states that contact with natural environments enriches the human
microbiome, promotes immune balance and protects from allergy and inflammatory …

Environmental exposures and mechanisms in allergy and asthma development

LB Murrison, EB Brandt, JB Myers… - The Journal of clinical …, 2019 - Am Soc Clin Investig
Environmental exposures interplay with human host factors to promote the development and
progression of allergic diseases. The worldwide prevalence of allergic disease is rising as a …

Rhinitis associated with asthma is distinct from rhinitis alone: the ARIA‐MeDALL hypothesis

J Bousquet, E Melén, T Haahtela, GH Koppelman… - Allergy, 2023 - Wiley Online Library
Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

[HTML][HTML] The impact of human activities and lifestyles on the interlinked microbiota and health of humans and of ecosystems

L Flandroy, T Poutahidis, G Berg, G Clarke… - Science of the total …, 2018 - Elsevier
Plants, animals and humans, are colonized by microorganisms (microbiota) and transiently
exposed to countless others. The microbiota affects the development and function of …

The skin microbiome: impact of modern environments on skin ecology, barrier integrity, and systemic immune programming

SL Prescott, DL Larcombe, AC Logan, C West… - World Allergy …, 2017 - Springer
Skin barrier structure and function is essential to human health. Hitherto unrecognized
functions of epidermal keratinocytes show that the skin plays an important role in adapting …

Perinatal and early-life nutrition, epigenetics, and allergy

N Acevedo, B Alashkar Alhamwe, L Caraballo, M Ding… - Nutrients, 2021 - mdpi.com
Epidemiological studies have shown a dramatic increase in the incidence and the
prevalence of allergic diseases over the last several decades. Environmental triggers …