Microbiome-based therapeutics
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
Microbiota-mediated colonization resistance: mechanisms and regulation
A dense and diverse microbial community inhabits the gut and many epithelial surfaces.
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …
The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
Microbiota, gut health and chicken productivity: what is the connection?
Gut microbiota and its relationship to animal health and productivity in commercial broiler
chickens has been difficult to establish due to high variability between flocks, which derives …
chickens has been difficult to establish due to high variability between flocks, which derives …
[HTML][HTML] A gut commensal-produced metabolite mediates colonization resistance to Salmonella infection
A Jacobson, L Lam, M Rajendram, F Tamburini… - Cell host & …, 2018 - cell.com
The intestinal microbiota provides colonization resistance against pathogens, limiting
pathogen expansion and transmission. These microbiota-mediated mechanisms were …
pathogen expansion and transmission. These microbiota-mediated mechanisms were …
Host microbiota constantly control maturation and function of microglia in the CNS
D Erny, AL Hrabě de Angelis, D Jaitin… - Nature …, 2015 - nature.com
As the tissue macrophages of the CNS, microglia are critically involved in diseases of the
CNS. However, it remains unknown what controls their maturation and activation under …
CNS. However, it remains unknown what controls their maturation and activation under …
Bacteroides Fragilis in the gut microbiomes of Alzheimer's disease activates microglia and triggers pathogenesis in neuronal C/EBPβ transgenic mice
Gut dysbiosis contributes to Alzheimer's disease (AD) pathogenesis, and Bacteroides strains
are selectively elevated in AD gut microbiota. However, it remains unknown which …
are selectively elevated in AD gut microbiota. However, it remains unknown which …
Stable engraftment of Bifidobacterium longum AH1206 in the human gut depends on individualized features of the resident microbiome
Live bacteria (such as probiotics) have long been used to modulate gut microbiota and
human physiology, but their colonization is mostly transient. Conceptual understanding of …
human physiology, but their colonization is mostly transient. Conceptual understanding of …
Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium
S Brugiroux, M Beutler, C Pfann, D Garzetti… - Nature …, 2016 - nature.com
Protection against enteric infections, also termed colonization resistance, results from
mutualistic interactions of the host and its indigenous microbes. The gut microbiota of …
mutualistic interactions of the host and its indigenous microbes. The gut microbiota of …
Diversity, stability and resilience of the human gut microbiota
Trillions of microbes inhabit the human intestine, forming a complex ecological community
that influences normal physiology and susceptibility to disease through its collective …
that influences normal physiology and susceptibility to disease through its collective …